Cassia auriculata and its role in infection / inflammation: A close look on future drug discovery.

The herbal plants contain various active compounds which have the ability to treat several human diseases without any side effects like cancer chemotherapeutic drugs used currently. It is reported that majority of the presently used drugs are derived from natural resources like plants or their products and hence, there is an urgent need to search for novel drugs from natural resources. Accordingly, the present study was designed to exploit an ethnomedicinally important plant Cassia auriculata Linn.

In vitro degradation, haemolysis and cytotoxicity study of Mg-0.4Ce/ZnO nanocomposites.

Magnesium is an ideal candidate for biodegradable implants, but the major concern is its uncontrollable degradation for application as a biomaterial. The in vitro corrosion and cytotoxicity of Mg-0.4Ce/ZnO (magnesium nanocomposites) were studied to determine its suitability as a biodegradable material.

Chronic Inflammatory-Modulating Potential of with Proinflammatory Cytokine IL-1beta and Its Anticancer Effect on Lung Cancer Cell Line.

Background: Inflammation is a key element in tumor progression, over time, persistent inflammation causes damage to DNA and leads to cancer. The relationship between chronic inflammation and tumor development is well established, blocking of which can help in cancer prevention and treatment in the future.

Objective: Hence, with this background, the present study aims to evaluate the anti-inflammatory and anticancer potential of Cassia auriculata (CA) solvent fractions through in silico and in vitro means, respectively.

and approaches to evaluate the bioactivity of Cassia auriculata L extracts.

The present study is an attempt to evaluate the anti-inflammatory and anticancer potentials of the plant (CA). The aerial parts of CA were subjected to solvent extraction, and the extracts were fractionised by gas chromatography and mass spectrometry analysis for its phytochemical content. The antiinflammatory activity of the extracts were confirmed by the IC value of 125.

In vitro evaluation of biodegradable nHAP-Chitosan-Gelatin-based scaffold for tissue engineering application.

The present study focuses on fabrication and characterisation of porous composite scaffold containing hydroxyapatite (HAP), chitosan, and gelatin with an average pore size of 250-1010 nm for improving wound repair and regeneration by Electrospinning method. From the results of -Ray Diffraction (XRD) study, the peaks correspond to crystallographic structure of HAP powder. The presence of functional group bonds of HAP powder, Chitosan and scaffold was studied using Fourier Transform Infrared Spectroscopy (FTIR).

Attenuation of cyclophosphamide induced toxicity by squalene in experimental rats.

Cyclophosphamide (CP) is a widely used antineoplastic drug, which could cause toxicity of the normal cells due to its toxic metabolites. In this study, the protective role of squalene (SQ) towards the tissue defense system in the toxicity induced by CP (150 mg/kg b.w.

Protective effect of Nardostachys jatamansi on oxidative injury and cellular abnormalities during doxorubicin-induced cardiac damage in rats.

Nardostachys jatamansi is a medicinally important herb of Indian origin. It has been used for centuries in the Ayurvedic and Unani systems of medicine for the treatment of various ailments. We have evaluated the effect of N.