Ethyl pyruvate improves skin flap survival after ischaemia reperfusion injury.

Background & Objectives: Reperfusion after ischaemia is detrimental to the tissues. The oxidative stress created and cytokines released are mostly responsible in this process. In this study, ethyl pyruvate, a known agent for its anti-inflammatory and antioxidant properties, was used to investigate the effects on ischaemia/reperfusion injury on skin island flaps in rats.

Tadalafil significantly reduces ischemia reperfusion injury in skin island flaps.

Introduction: Numerous pharmacological agents have been used to enhance the viability of flaps. Ischemia reperfusion (I/R) injury is an unwanted, sometimes devastating complication in reconstructive microsurgery. Tadalafil, a specific inhibitor of phosphodiesterase type 5 is mainly used for erectile dysfunction, and acts on vascular smooth muscles, platelets and leukocytes.

Preventive effect of dexmedetomidine in ischemia-reperfusion injury.

Background: The aim of this study was to evaluate the effects of dexmedetomidine on ischemia-reperfusion injury of epigastric island flaps of rats.

Methods: Eighty Wistar rats were divided into 4 groups. After the flap elevation, in group 1, the flaps were sutured back without ischemic insult.

Nasal hair matrix cyst mimicking dermoid cyst.

Dermoid cysts are primarily observed in the head and neck region. Nasal dermoids are uncommon. The terms nasal dermoid, nasal epidermoid, and nasal sebaceous cysts are used interchangeably by clinicians.

Manually adjustable conformer for socket reconstruction: a practical and simple method.

Loss of an eye can be a traumatic experience for a patient. The subsequent formation of scar tissue prevents the performance of daily function and, more important, is accompanied by social isolation. To ensure a permanent prosthesis, appropriate closure of the socket is proposed.

Maxillary sinus lipoma: an unanticipated diagnosis.

Subcutaneous tissue gives rise to numerous lesions such as lipoma, the most common benign soft tissue tumors. Lipoma is seen only extremely rarely in osseous units. In addition, craniofacial involvement of intraosseous lipoma may be misdiagnosed as a fibroosseous tumour such as fibrous dysplasia.

Struggling with ischemia reperfusion injury.

Ischemia reperfusion (I/R) injury is a complicated injury that compels either the patient or the practitioner. In the literature, there still is a debate over how to manage the injury. Typically, no single treatment is feasible.