Long-acting contraceptive agents: levonorgestrel esters of unsaturated acids.

Esters of levonorgestrel (13 beta-ethyl-17 beta-ethynyl-17 beta-hydroxygon-4-en-3-one) with a variety of unsaturated carboxylic acids have been synthesized for evaluation as potential long-acting, injectable contraceptive agents.

[Aicardi syndrome].

The association in young girls of flexion spasms of early beginning, partial or total agenesis of the corpus callosum, severe chororetinopathy and frequent skeletal anomalies is known as the Aicardi syndrome. On occasion of two observations a review of the literature is made.

[Ventricular rigidity in mitral stenosis measured by an echocardiographic and hemodynamic method].

Ten patients with mitral stenosis underwent right and left heart catheterization. In order to assess the diastolic properties of these ventricles an hemodynamic-echocardiografic techniques was employed. Left ventricular pressure and an echocardiogram of the body of the left ventricle were simultaneously registered.

[The use of microcomputers in the processing of complex hemodynamic data].

The use of a low-cost microcomputer in the clinical study of left ventricular diastolic function is described. Both left ventricular filling and compliance were studied by means of the simultaneous recording of left ventricular pressure and an echocardiogram displaying ventricular dimensions. A program was written to calculate ventricular volume every 40 msec and a volume-time diagram was obtained.