Predictive value of thrombocytopenia for bloodstream infection in patients with sepsis and septic shock.

Background: Thrombocytopenia is common in patients with sepsis and septic shock.

Aim: To analyse the decrease in the number of platelets for predicting bloodstream infection in patients with sepsis and septic shock in the intensive care unit.

Methods: A retrospective analysis of patients admitted with sepsis and septic shock in Xingtai People Hospital was revisited.

Effects of Astragalus polysaccharide on the erythroid lineage and microarray analysis in K562 cells.

Ethnopharmacological Relevance: Astragalus polysaccharide (APS), obtained from Astragalus membranaceus, displays a range of activities in many systems, including the promotion of immune responses, anti-inflammation, and the protection of vessels. It possesses potent pharmacological activity on differentiation to the erythroid lineage.

Aim Of The Study: To investigate the effects of APS on the erythroid differentiation and the mechanism of action by microarray analysis in K562 cells.

Protective role of supplement with foreign Bifidobacterium and Lactobacillus in experimental hepatic ischemia-reperfusion injury.

Background And Aim: Intestinal microflora play a crucial role in some severe liver diseases. The purpose of this study was to evaluate the effects of a Lactobacillus strain and a Bifidobacterium strain on ischemia-reperfusion (I/R) liver injury.

Methods: Rats were divided into six groups.

Effects of Salvia miltiorrhiza on intestinal microflora in rats with ischemia/reperfusion liver injury.

Background: Hepatic ischemia/reperfusion injury may induce intestinal microflora imbalance. Salvia miltiorrhiza is effective in promoting blood circulation and counteracting peroxidation in tissues. The aim of the present study was to determine the effects of Salvia miltiorrhiza on intestinal microflora, endotoxemia, and bacterial translocation in rats with hepatic I/R injury.

[Preliminary comparative study on the effects of early enteral supplementation of synbiotics on severely burned patients].

Objective: To investigate the influence of early enteral nutrition with synbiotics on the plasma endotoxin level, the nutritional state, the inflammatory response and the incidence of infectious complications in severely burned patients.

Methods: Randomized double blind and control method was employed im the study. Forty severely burned patients were randomly divided into A and B groups with 20 in each group.

Effect of artificial liver support system on patients with severe viral hepatitis: a study of four hundred cases.

Aim: To assess the effect of artificial liver support system (ALSS) on patients with severe viral hepatitis, who were divided into treatment group and control group.

Methods: Four hundred in-hospital patients enrolled during 1995-2003 who received ALSS therapy were studied as the treatment group. Four hundred in-hospital patients enrolled during 1986-1994 who received other medical therapies served as the control group.

[Dynamic variability of intestinal flora and endotoxin in rat with fulminate hepatic failure].

Objective: To investigate the dynamic variability of intestinal flora and endotoxins in rats with fulminate hepatic failure.

Methods: Establishing the fulminate hepatic failure models by intraperitoneal injection of Galactosamine. Forty Sprague-Dawley rats were divided into three groups: group A (n=10) were killed at the beginning of the experiment as control; while Group B (n=12) and C (n=18), the fulminate hepatic failure models, were killed 24 and 48 hours respectively after successful induction.

[Study of severe hepatitis treated with a hybrid artificial liver support system].

Objectives: To evaluate the efficacy of a hybrid artificial liver support system in the treatment of chronic severe hepatitis.

Methods: The hybrid artificial liver support system (HALSS) consisted of a bioreactor containing more than 5 x 10(9) porcine hepatocytes and plasma exchange device. 15 patients with chronic severe viral hepatitis were treated with the hybrid system.