Associations between body weight trajectories and neurodevelopment outcomes at 24 months corrected age in very-low-birth-weight preterm infants: a group-based trajectory modelling study.

Introduction: This study aimed to explore the relationship between the trajectories of body weight (BW) -scores at birth, discharge, and 6 months corrected age (CA) and neurodevelopmental outcomes at 24 months CA.

Methods: Conducted as a population-based retrospective cohort study across 21 hospitals in Taiwan, we recruited 3,334 very-low-birth-weight (VLBW) infants born between 2012 and 2017 at 23-32 weeks of gestation. Neurodevelopmental outcomes were assessed at 24 months CA.

Predicting early mortality and severe intraventricular hemorrhage in very-low birth weight preterm infants: a nationwide, multicenter study using machine learning.

Our aim was to develop a machine learning-based predictor for early mortality and severe intraventricular hemorrhage (IVH) in very-low birth weight (VLBW) preterm infants in Taiwan. We collected retrospective data from VLBW infants, dividing them into two cohorts: one for model development and internal validation (Cohort 1, 2016-2021), and another for external validation (Cohort 2, 2022). Primary outcomes included early mortality, severe IVH, and early poor outcomes (a combination of both).

Unmasking air quality: A novel image-based approach to align public perception with pollution levels.

In the quest to reconcile public perception of air pollution with scientific measurements, our study introduced a pioneering method involving a gradient boost-regression tree model integrating PM concentration, visibility, and image-based data. Traditional stationary monitoring often falls short of accurately capturing public air quality perceptions, prompting the need for alternative strategies. Leveraging an extensive dataset of over 20,000 public visibility perception evaluations and over 8,000 stationary images, our models effectively quantify diverse air quality perceptions.

Small blood stem cells for enhancing early osseointegration formation on dental implants: a human phase I safety study.

Background: Small blood stem cells (SB cells), isolated from human peripheral blood, demonstrated the ability to benefit bone regeneration and osseointegration. The primary goal of our study is to examine the safety and tolerability of SB cells in dental implantation for human patients with severe bone defects.

Methods: Nine patients were enrolled and divided into three groups with SB cell treatment doses of 1 × 10, 1 × 10, and 1 × 10 SB cells, and then evaluated by computed tomography (CT) scans to assess bone mineral density (BMD) by Hounsfield units (HU) scoring.

Evaluation of the implant stability and the marginal bone level changes during the first three months of dental implant healing process: A prospective clinical study.

Achievement of adequate implant stability is one of the determinants for long-term successful osseointegration. Resonance frequency analysis was developed to monitor implant stability and is now a well-recognized, non-invasive tool for determining the appropriate time for functional loading. However, there have been few studies with continuous evaluation and comparison of implant stability and marginal bone level changes between two different macro designs and clinical situations during the implant healing process.

[Experiment study of infusing tPA in retinal vein for treatment of retinal vein occlusion].

Objective: To Investigate the effectiveness and complications of injection of tissue plasminogen activator into a retinal vein for treatment of retinal vein occlusion via micropuncture of the retinal vein.

Methods: Thirty miniature pigs (one eye of each pig) were produced photodynamic thrombi of retinal vein by injecting Rose bengal (20 mg/kg) into the ear vein, and randomly divided into three groups: 1. control (n = 8), 2.

[Experimental retinal vein occlusion induced by photodynamic approach].

Objective: To develop a new photochemical method of experimental retinal vein occlusion and investigate the morphologic and histologic changes in the retina.

Methods: After intravenous injection of rose Bengal, the vessels next to the disc of miniature pigs in the experiment group (n = 15) were exposed to an endo-illuminator for 15 minutes. As a control group, the vessels next to the disc of each pig were exposed to the endo-illuminator without rose Bengal injection.