[Diosgenin alleviates NAFLD induced by a high-fat diet in rats via mTOR/SREBP-1c/HSP60/MCAD/SCAD signaling pathway].

This study aims to observe the effects of diosgenin on the expression of mammalian target of rapamycin(mTOR), sterol regulatory element-binding protein-1c(SREBP-1c), heat shock protein 60(HSP60), medium-chain acyl-CoA dehydrogenase(MCAD), and short-chain acyl-CoA dehydrogenase(SCAD) in the liver tissue of the rat model of non-alcoholic fatty liver disease(NAFLD) and explore the mechanism of diosgenin in alleviating NAFLD. Forty male SD rats were randomized into five groups: a control group, a model group, low-(150 mg·kg~(-1)·d~(-1)) and high-dose(300 mg·kg~(-1)·d~(-1)) diosgenin groups, and a simvastatin(4 mg·kg~(-1)·d~(-1)) group. The rats in the control group were fed with a normal diet, while those in the other four groups were fed with a high-fat diet.

[Effect of diosgenin on mTOR/FASN/HIF-1α/VEGFA expression in rats with non-alcoholic fatty liver disease].

The present study aimed to investigate the effect of diosgenin on mammalian target of rapamycin(mTOR), fatty acid synthase(FASN), hypoxia inducible factor-1α(HIF-1α), and vascular endothelial growth factor A(VEGFA) expression in liver tissues of rats with non-alcoholic fatty liver disease(NAFLD) and explore the mechanism of diosgenin on lipogenesis and inflammation in NAFLD. Forty male SD rats were divided into a normal group(n=8) fed on the normal diet and an experimental group(n=32) fed on the high-fat diet(HFD) for the induction of the NAFLD model. After modeling, the rats in the experimental group were randomly divided into an HFD group, a low-dose diosgenin group(150 mg·kg~(-1)·d~(-1)), a high-dose diosgenin group(300 mg·kg~(-1)·d~(-1)), and a simvastatin group(4 mg·kg~(-1)·d~(-1)), with eight rats in each group.

Occupational evaluation of community-based psychiatric rehabilitation outcomes in individuals with severe mental illnesses: A ten-year retrospective study.

Background: There is a lack of research on the effect of community-based psychiatric rehabilitation programs (CBPRs) in individuals with severe mental illness. This research used data from a retrospective study to examine the effect of a CBPR in a community rehabilitation center.

Materials And Methods: Clinical outcomes measures from a retrospective study were collected.

Recovery Programs for People With Mental Illness in Taiwan: A Feasibility Study.

Importance: Most recovery programs have been developed in Western countries. This study explores the cultural adaptation of a recovery program to a non-Western country.

Objective: To test the feasibility of a recovery group developed for people with mental illness in Taiwan.

Heterozygous/dispermic complete mole confers a significantly higher risk for post-molar gestational trophoblastic disease.

Hydatidiform moles are classified at the genetic level as androgenetic complete mole and diandric-monogynic partial mole. Conflicting data exist whether heterozygous complete moles are more aggressive clinically than homozygous complete moles. We investigated clinical outcome in a large cohort of hydatidiform moles in Chinese patients with an emphasis on genotypical correlation with post-molar gestational trophoblastic disease.

Removal of uranium(VI) from aqueous solution using iminodiacetic acid derivative functionalized SBA-15 as adsorbents.

Three different functional SBA-15 were prepared by a post-grafting method using three iminodiacetic acid derivatives of ethylenediaminetriacetic acid (ED3A), diethylenetriaminetetraacetic acid (DT4A), and 1,2-cyclohexylenedinitrilotriacetic acid (CyD3A), which were used as adsorbents for removal of uranium(vi) from aqueous solution. These materials were characterized by FT-IR, NMR, TEM, nitrogen adsorption/desorption experiments, and elemental analysis. The effect of pH, ionic strength, contact time, solid-liquid ratio, initial metal ion concentration, temperature, and coexisting ions on uranium(vi) sorption behaviors of the functionalized SBA-15 was studied.

[Niche characteristics of common microalgae communities in prawn-aquaculture pond in terms of water temperature, salinity, nitrogen, and phosphorus resources].

A 4-factorial (water temperature, salinity, nitrogen, and phosphorus) experiment was designed to study the niche characteristics of four common microalgae communities in prawn-aquaculture pond. The results showed that the niche breadth was the greatest for Cryptomonas erosa in temperature and salinity resources (0.980 and 0.

Synthesis, infrared and fluorescence spectra of lanthanide complexes with a new amide-based 1,3,4-oxadiazole derivative.

A new amide-based 1,3,4-oxadiazole derivative ligand 2,5-bis[2-(N,N-diethyl-1'-oxopropylamide)phenyl]-1,3,4-oxadiazole (L) and its complexes, Ln(NO3)3L (Ln=La, Eu, Gd, Tb, Er), were synthesized. The complexes were characterized by elemental analysis, infrared spectra and conductivity. The lanthanide ions were coordinated by O atoms from CO.

Genotypes and viremia of hepatitis B and D viruses are associated with outcomes of chronic hepatitis D patients.

Background & Aims: Genotypes and viremia of hepatitis D virus (HDV) and hepatitis B virus (HBV) may be associated with outcomes. This study evaluated the impact of viral genotypes and viremia on outcomes of dual HBV and HDV infection.

Methods: Viremia and viral genotypes were analyzed in 194 consecutive chronic hepatitis B patients with HDV superinfection and correlated with outcomes.

Terminal group effects on the fluorescence spectra of Eu(III) nitrate complexes with a family of amide-based 1,10-phenanthroline derivatives.

Four ligands 1,10-phenanthroline-5,6-bis(N,N-dibenzyl-1'-oxopropylamide) (La) 1,10-phenanthroline-5,6-bis(N-methyl-N-benzyl-1'-oxopropylamide) (Lb) 1,10-phenanthroline-5,6-bis(N-benzyl-1'-oxopropylamide) (Lc) and 1,10-phenanthroline-5,6-bis(N,N-diethyl-1'-oxopropylamide) (Ld), and their lanthanide(III) (La and Eu) complexes were synthesized. The complexes were characterized by elemental analysis, IR, fluorescence spectroscopy and conductivity. The lanthanide atoms are coordinated by O atoms from C=O, Ar-O -C and N atoms from phen With the difference of the ligands, the fluorescent intensities of the Eu(III) complexes vary regularly in the THF solution.