Publications by authors named "Su-Zi Yoo"

Article Synopsis
  • Statins, like atorvastatin, can help prevent heart disease but may cause muscle issues and mitochondrial problems.
  • A study with Wistar rats found that combining atorvastatin treatment with aerobic exercise improved glucose tolerance, muscle strength, and reduced muscle damage compared to rats only on atorvastatin.
  • Exercise training also appears to help preserve mitochondrial function and increase certain protective proteins in the muscles affected by atorvastatin.
View Article and Find Full Text PDF

Aging is associated with vulnerability to cardiovascular diseases, and mitochondrial dysfunction plays a critical role in cardiovascular disease pathogenesis. Exercise training is associated with benefits against chronic cardiac diseases. The purpose of this study was to determine the effects of aging and treadmill exercise training on mitochondrial function and apoptosis in the rat heart.

View Article and Find Full Text PDF

This study aimed to determine the effects of a single bout exercise on mitochondria-mediated apoptotic signaling in cardiac and skeletal muscles. Fischer 344 rats (4 months old) were randomly divided into the control or a single bout of exercise group (n=10 each). The rats performed a single bout of treadmill exercise for 60 min.

View Article and Find Full Text PDF

Purpose: Chemotherapy is associated with the side effects including damage to the mitochondrial DNA. Doxorubicin (DOX) serves as a chemotherapeutic agent for the patients with breast cancer or prostate cancer. DOX causes muscle weakness and fatigue.

View Article and Find Full Text PDF
Article Synopsis
  • - This study examined how a single session of exercise impacts mitochondrial function, dynamics, and mitophagy in the heart and skeletal muscles of Fischer 344 rats.
  • - The rats that exercised showed improved mitochondrial oxygen respiration and calcium retention, but mitochondrial fusion and fission were unchanged, with varied effects on mitophagy across different muscle types.
  • - The findings suggest that aerobic exercise enhances certain aspects of mitochondrial function without affecting the overall dynamics or the process of cleaning up damaged mitochondria.
View Article and Find Full Text PDF
Article Synopsis
  • * This study examined how aging affects mitochondrial function in the hearts of different age groups of male Fischer 344 rats.
  • * Results showed that aging reduces essential mitochondrial proteins and increases reactive oxygen species production, while decreasing calcium retention capacity, indicating that mitochondrial dysfunction is a key factor in age-related heart issues.
View Article and Find Full Text PDF
Article Synopsis
  • Obesity leads to changes in skeletal muscle and increased apoptosis (cell death) associated with mitochondria, which can negatively affect muscle function.
  • A study used four groups of mice to examine how exercise influences muscle structure and cell death in the context of obesity induced by a high-fat diet.
  • The findings indicate that exercise helps improve muscle structure and reduces apoptosis in obese mice, highlighting its potential protective effects on skeletal muscle health.
View Article and Find Full Text PDF

Sarcopenia is an age-associated decline of skeletal muscle mass and function and is known to lead to frailty, cachexia, osteoporosis, metabolic syndromes, and death. Notwithstanding the increasing incidence of sarcopenia, the molecular and cellular mechanisms driving age-related sarcopenia are not completely understood. This article reviews current definitions of sarcopenia, its potential mechanisms, and effects of exercise on sarcopenia.

View Article and Find Full Text PDF

A PHP Error was encountered

Severity: Warning

Message: fopen(/var/lib/php/sessions/ci_session53p4q1lgs6iahhjvd6lbf2ov6i1b6t4m): Failed to open stream: No space left on device

Filename: drivers/Session_files_driver.php

Line Number: 177

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once

A PHP Error was encountered

Severity: Warning

Message: session_start(): Failed to read session data: user (path: /var/lib/php/sessions)

Filename: Session/Session.php

Line Number: 137

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once