Publications by authors named "Su-Xia Yao"

Background: Brucellosis is a worldwide zoonotic disease caused by Brucella spp. Brucella invades the body through the skin mucosa, digestive tract, and respiratory tract. However, only a few studies on human spontaneous abortion attributable to Brucella have been reported.

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Objective: To investigate whether the RelE toxin protein of mycobacterium tuberculosis has a growth inhibition effect on lung cancer A-549 cell.

Methods: The complete open-reading frame sequences of RelE, RelB and RelBE genes were amplified by PCR with using M. tuberculosis H37Rv genomic DNA as the template.

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Objective: To test the effect of Rv0901 gene of Mycobacterium tuberculosis on the activity of mice macrophages.

Methods: Peritoneal macrophages of mice were isolated and transfected with pcDNA3. 1 or pcDNA3.

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Article Synopsis
  • The study aimed to explore the interaction between two hypothetical proteins, Rv1246c and Rv1247c, in Mycobacterium tuberculosis.
  • Using PCR, the full gene sequences of Rv1246c and Rv1247c were amplified and cloned into specific vectors to create recombinant plasmids for yeast transformation.
  • The successful growth of yeast cells on selective plates and positive beta-galactosidase activity confirmed that Rv1246c and Rv1247c interact with each other in yeast.
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Objective: The mechanism by which M.tuberculosis persists and survives in host macrophage is not fully understood, however, the M. tuberculosis chromosome-encoded TA loci perform functions possibly of signaling to these processes.

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