A 6-Year Follow-up of a Chinese Child with Homozygous β-Thalaasemia and a Heterozygous Mutation.

Patients with the genotype of β/β for β-thalassemia (β-thal) usually behave as β-thal major (β-TM) phenotype which is transfusion-dependent. The pathophysiology of β-thal is the imbalance between α/β-globin chains. The degree of α/β-globin imbalance can be reduced by the more effective synthesis of γ-globin chains, and increased Hb F levels, modifying clinical severity of β-TM.

Severe Hb H Disease Caused by Hb Zürich-Albisrieden (: c.178G>C): Another Case Report.

Hb Zürich-Albisrieden, [α59(E8)Gly→Arg, : c.178G>C] is a rare and highly unstable α-globin chain variant. The involved mutation has been reported in both and genes.

Hb Wanjiang: A New β-Globin Chain Variant with Two Amino Acid Substitutions (: c.255_264delinsTTTTTCTCAG).

We report a new hemoglobin (Hb) variant that we have named Hb Wanjiang (: c.255_264delinsTTTTTCTCAG). We identified this variant in a Chinese man by the next-generation sequencing (NGS) method.

Predicting the success of vaginal birth after caesarean delivery: a retrospective cohort study in China.

Objectives: To develop a nomogram to predict the likelihood of vaginal birth after caesarean section (VBAC) among women after a previous caesarean section (CS).

Design: A retrospective cohort study.

Setting: Two secondary hospitals in Guangdong Province, China.

Retrospective review on obstetric cases of critically ill and dead patients in Dongguan.

This retrospective analysis was set to understand the epidemiological status of the critically ill obstetric patients in Dongguan city, Guangdong, China. Understanding the risk factors for the death cases can provide scientific evidences for future preventive strategies to decrease the maternal mortality rate. This retrospective included the statistical data and clinical data on the cases of critically ill and dead obstetric patients admitted to Dongguan People's Hospital and Dongguan Maternal & Child Health Hospital from September 1st, 2009 to August 31st, 2013.