[Effects of Xinjierkang on two kidney one clip-induced hypertension and target organ injury in rats].

Objective: To investigate the effects of Xinjierkang on two kidney one clip -induced hypertension and target organ injury in rats.

Methods: Two kidney one clip-induced hypertension rats model was established. Rats were divided into control group, model group, Xinjierkang group, and fosinopril group.

[Effects of a compound Chinese medicine Xinji' erkang on isoproterenol-induced ventricular remodeling in mice].

Objective: To investigate the effects of Xinji' erkang (XJEK), a compound Chinese herbal medicine, on isoproterenol-induced ventricular remodeling in mice.

Methods: Isoproterenol was given subcutaneously (1 mg/kg, twice per day for 7 d) to induce ventricular remodeling in mice. Mice were divided into normal control group, model group, XJEK low-, medium- and high- dose groups, XJEK water layer group, XJEK n-butanol layer group and metoprolol group.