Publications by authors named "Su-Gen Zeng"
[Genetic Polymorphisms in Wnt Signaling Pathway and Acute Leukemia].
Sichuan Da Xue Xue Bao Yi Xue Ban
May 2015
Article Synopsis
- The study aimed to assess how specific gene polymorphisms in the Wnt signaling pathway affect the risk and treatment outcomes of acute leukemia, focusing on three specific SNPs in the CTNNB1, AXIN2, and SFRP1 genes.
- Bone marrow and blood samples from leukemia patients and healthy controls were analyzed using high-resolution melting methods, with statistical tests performed to compare genetic variations and their associations with clinical features and chemotherapy outcomes.
- Results indicated no significant genetic differences for CTNNB1 and SFRP1 between patients and controls, but the AXIN2 variant affected leukemia type and patient outcomes, with A allele carriers showing better clinical results, including higher platelet counts and remission rates after treatment.
Background: To establish a reliable correction method for automated hemoglobin (HGB) measurement by minimizing the interference from blood high triglyceride (TG).
Methods: Fifty whole blood samples and 50 plasma samples containing variable TG concentrations were used to determine the centrifugation speed and time. Complete blood cell counts (CBCs) were performed by an automated hematology analyzer for 102 blood samples, in which high-level TG were artificially added.
[Clinical application of review criteria for complete blood analysis].
Zhonghua Yi Xue Za Zhi
June 2010
Objective: To evaluate the review criteria for complete blood analysis.
Methods: total of 8820 blood samples taken at our hospital were detected both by the Sysmex XE-2100 automated blood cell analyzer and double-blind method microscopy. The performance of two review criteria were evaluated by statistical analysis.