Publications by authors named "Su Yuan"

Introduction: The intestinal dysfunction plays an important role in the decreased growth performance of broiler chickens under high stocking density. Gut microbiota plays an important role in maintaining intestinal health. However, the modulation pathway of gut microbiota by regulating the intestinal barrier and histomorphology remains unknown.

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Introduction: This study aimed to identify suitable plants for remediating metal pollution in copper tailing soil and supporting ecological reclamation in Dongchuan, Yunnan, focusing on three major mining regions: Tangdan, Yinmin, and Lanniping.

Methods: The Nemerow comprehensive pollution index was employed to evaluate the metal contamination levels, and the enrichment and transfer capacities of the dominant plants for Cd, Cu, Pb, and Zn were analyzed to identify remediation candidates.

Results: The findings revealed severe pollution in the copper tailing soil, with Cu as the primary pollutant, and with a pollution rate of 77.

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In this report, a 69-year-old man with fever, thrombocytopenia, and hepatic and renal dysfunction presented to our hospital. His disease progression was rapid, and he became unconscious. The patient was diagnosed with severe fever with thrombocytopenia syndrome (SFTS).

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Chronic kidney disease (CKD) is a major health concern, with renal interstitial fibrosis (RIF) as a key feature. Effective management of RIF is crucial for treating CKD. Yiqi Juanshen decoction (YQJSD), as traditional Chinese medicine, has shown promising results in CKD treatment.

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A biosensor based on solid-state nanochannels of anodic aluminum oxide (AAO) membrane for both electrochemical and naked-eye detection of microRNA-31 (MiR-31) is proposed. For this purpose, MoS nanosheets, which possess different adsorption capabilities to single-stranded and double-stranded nucleic acids, are deposited onto the top surface of the AAO membrane. Moreover, multi-functional DNA nanostructure have been designed by linking a G-rich sequence for folding to a G-quadruplex at three vertices and a complementary sequence of MiR-31 at the other one vertex of a DNA tetrahedron.

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Thrombosis is an important cause of morbidity and mortality worldwide. Pregnancy is a hypercoagulable state, and thrombotic complications in pregnancy are a major cause of maternal and fetal morbidity and mortality. Current guidelines support the selective use of aspirin, heparin, and warfarin in pregnant women.

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Periodontal ligament fibroblasts (PDLFs) play a crucial role in the etiology of periodontitis and periodontal tissue regeneration. In healthy periodontal tissues, PDLFs maintain the homeostasis of periodontal soft and hard tissues as well as the local immune microenvironment. PDLFs also have the potential for multidirectional transdifferentiation and are involved in periodontal tissue regeneration.

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Endoscopes, a minimally invasive medical tool, are susceptible to impaired visibility due to the adhesion of biological fluids. However, traditional self-cleaning coatings face limitations in terms of transparency and sustainability, making it difficult to apply them to lenses. Inspired by the phospholipid layer of the eye, a reversible lubricating layer (RL-layer) with low-adhesion and high-transparency properties is reported.

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Article Synopsis
  • The study aimed to evaluate how preoperative use of renin-angiotensin system inhibitors (RASi) affects kidney function and patient outcomes after coronary artery bypass grafting (CABG).
  • Researchers analyzed data from 33,884 CABG patients over nearly a decade, looking specifically at the rates of acute kidney injury (AKI) and mortality.
  • Results indicated that patients using RASi pre-surgery had a specific incidence of AKI, with subgroup analyses further examining the effects in patients with hypertension and heart failure.
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Solid-state nanochannels (SSN) have great development potential as a biosensing interface. The integration of two-dimensional nanomaterials with nanochannels endows SSN with diverse properties, including distinguishing DNA nanostructures. In this study, by modifying MoS nanosheets, the outer surface of SSN could be endowed with robust adsorption properties for single-stranded DNA.

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Listeria monocytogenes serotypes 1/2a, 1/2b, and 4b are implicated in over 90 % of human listeriosis cases; however, information regarding the serotype-specific survival of L. monocytogenes on apples remains limited. This study evaluated the survival dynamics of these serotypes, using two sets of strains, on Granny Smith apples (GSA) and examined the impact of wax-coating on their survivability during storage.

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Recent foodborne outbreaks and recalls involving and -contaminated peaches have caused significant economic losses to the peach industry. This study evaluated the effectiveness of chlorine, a commonly used sanitizer in the fresh produce industry, against and and its ability to control cross-contamination in fresh peaches. Peaches inoculated with or (~6 log CFU/peach) were treated with 50-150 mg/L of free chlorine (FC, pH6.

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Introduction: This study aims to determine whether paravertebral block (PVB) provides better postoperative analgesia, lower incidence of complications and faster recovery compared with local anaesthetic wound infiltration for school-aged children undergoing cardiac surgery with cardiopulmonary bypass via thoracotomy.

Method And Analysis: This is a single-centre, randomised controlled trial. We will enrol 100 children aged 6-14 years with atrial or ventricular septal defects scheduled for thoracotomy cardiac surgery with cardiopulmonary bypass.

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Article Synopsis
  • This study investigates how voriconazole (VRC) levels are distributed in patients with liver dysfunction, emphasizing the need for careful monitoring of drug levels in this population.
  • It analyzes medical records of 102 hospitalized patients and identifies factors like age, liver disease severity (Child-Pugh score), CRP levels, and bilirubin that affect VRC concentrations.
  • The findings suggest a high rate of VRC-related side effects and propose that dosage adjustments, including therapeutic drug monitoring, are crucial for older patients and those with severe infections or low albumin levels to avoid toxicity.
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Background: Trabectedin (Tbt) is an alkylating agent prescribed for soft tissue sarcomas after treatment failure of first line agents. While cardiomyopathy can occur with Tbt treatment after anthracycline exposure, Tbt-induced fulminant myocardial cytotoxic injury in the setting of other systemic cytotoxicity associated with Tbt has not been reported.

Case Presentation: 51-year-old female with hypertension, hyperlipidemia, metastatic leiomyosarcoma with progression of disease despite several lines of chemotherapy including doxorubicin-based therapy was started on Trabectedin (Tbt) 5 days prior to presentation with symptoms of fever, myalgias, arthralgias, and palpitations.

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Article Synopsis
  • The text discusses improvements in treating congenital heart disease through enhanced recovery after surgery (ERAS) programs, which incorporate multimodal pain management to reduce pain and improve patient outcomes.
  • It highlights the limitations of traditional high-dose opioid pain control and the shift towards nonopioid analgesics and regional anesthesia to limit complications.
  • A network meta-analysis (NMA) will be conducted on existing randomized controlled trials to compare various pain management strategies in pediatric cardiac surgery, emphasizing the need for standardized practices.
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Foodborne illnesses caused by Salmonella bacteria pose a significant threat to public health. It is still challenging to detect them effectively. Herein, biotemplated Janus disk-shaped magnetic microrobots (BJDMs) based on diatomite are developed for the highly efficient detection of Salmonella in milk.

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In the post-COVID-19 era, treatment options for potential SARS-CoV-2 outbreaks remain limited. An increased incidence of central nervous system (CNS) disorders has been observed in long-term COVID-19 patients. Understanding the shared molecular mechanisms between these conditions may provide new insights for developing effective therapies.

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Article Synopsis
  • Recent advancements in surgical techniques have shifted focus to improving postoperative recovery quality, with patient hospital stay length being a key recovery indicator.
  • A study on children with Ebstein Anomaly who had corrective surgery identified six predictors influencing how long they stayed in the hospital, using data from Fuwai Hospital between 2009 and 2021.
  • Results showed that younger age, certain surgical classifications, and specific treatments like dexamethasone impacted hospital discharge times, with longer stays linked to higher adverse outcomes and increased healthcare costs.
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Tubular injury and oxidative stress are involved in the pathogenesis of diabetic kidney disease (DKD). Astragaloside IV (ASIV) is a natural antioxidant. The effects and underlying molecular mechanisms of ASIV on DKD have not been elucidated.

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U6 snRNA is one of the uridine-rich non-coding RNAs, abundant and stable in various cells, function as core particles in the intron-lariat spliceosome (ILS) complex. The Increased Level of Polyploidy1-1D (ILP1) and NTC-related protein 1 (NTR1), two conserved disassembly factors of the ILS complex, facilitates the disintegration of the ILS complex after completing intron splicing. The functional impairment of ILP1 and NTR1 lead to increased U6 levels, while other snRNAs comprising the ILS complex remained unaffected.

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Article Synopsis
  • A study was conducted to determine the relationship between intra-operative urine output (UO) and the risk of acute kidney injury (AKI) in children with congenital heart disease undergoing cardiac surgery.
  • The research involved 1,184 children, revealing that 23.1% developed AKI post-surgery, with varying stages of severity.
  • The findings indicated no significant link between intra-operative UO and overall AKI, although there was a notable association between UO and moderate-to-severe AKI cases.
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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a lipid-enveloped virus that acquires its lipid bilayer from the host cell it infects. SARS-CoV-2 can spread from cell to cell or from patient to patient by undergoing assembly and budding to form new virions. The assembly and budding of SARS-CoV-2 is mediated by several structural proteins known as envelope (E), membrane (M), nucleoprotein (N), and spike (S), which can form virus-like particles (VLPs) when co-expressed in mammalian cells.

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In the context of the rapid progress of global urbanization, the massive encroachment of social landscapes into ecological and productive landscapes has led to a series of environmental problems. Furthermore, analyzing the landscape resilience could effectively reveal the sustainable development ability of the urban landscape. This study establishes a social-ecological productive landscape resilience (SEPLR) evaluation system and reveals trade-offs and synergies between different landscape types and resilience.

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Objectives: Given the widespread use of Chinese patent medicines (CPMs) in combination with 5-aminosalicylic acid (5-ASA) for Ulcerative colitis (UC) patients, this study aimed to evaluate the efficacy and safety of nine CPMs combined with 5-ASA in the treatment of UC.

Methods: A systematic literature search was conducted in eight databases from inception to May 2023 to identify eligible RCTs evaluating the effects of CPM combined with 5-ASA for the treatment of UC. The methodological quality of the included RCTs was assessed using the Cochrane risk of bias tool in Review Manager 5.

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