Three-dimensional numerical simulation and experimental validation of airborne ground-penetrating radar based on CNCS-FDTD method under undulating terrain conditions.

Traditional Finite Difference Time Domain (FDTD) approaches face challenges with increased computational demands and errors as terrain complexity and flight altitude rising. This study introduces the Crank-Nicolson-Cycle-Sweep-FDTD (CNCS-FDTD) method, enhancing airborne ground penetrating radar (GPR) simulations over undulating terrains. CNCS-FDTD, as an unconditionally stable implicit algorithm, overcomes these by allowing larger time steps without the constraints of the Courant-Friedrichs-Lewy (CFL) condition.

Using betaxolol for the prevention of paronychia induced by epidermal growth factor receptor inhibitors: a case-control cohort study.

Background: High rates of posttreatment discomfort, infection, recurrence, and increased time to return to work have been noted after nail plate avulsion resulting from epidermal growth factor receptor tyrosine kinase inhibitor(EGFR-TKI)-induced paronychia, which may even interrupt the course of treatment for EGFR-TKI therapy. Thus, we conducted this study to determine how effectively a topical β-blocker, betaxolol, prevents EGFR-TKI-induced paronychia.

Methods: This case-control cohort study included a total of 131 non-small-cell lung cancer patients.

Simvastatin inhibits the proliferation of HL-60 clone 15- derived eosinophils by inducing the arrest of the cell cycle in the G1/S phase.

Eosinophils and their granular proteins are crucial for combating allergic airway diseases. Eosinophils derived from HL-60 clone 15 (HC15) cells have been established as a feasible alternative cell model for human primary eosinophils. Simvastatin, a cholesterol-lowering agent, has been shown to exhibit anti-inflammatory and anti-allergic effects.

Simvastatin Inhibits IL-5-Induced Chemotaxis and CCR3 Expression of HL-60-Derived and Human Primary Eosinophils.

IL-5-induced chemotaxis of eosinophils is an important feature of allergic airway inflammatory diseases. Simvastatin, a lipid lowering agent, has been shown to exhibit anti-inflammatory and anti-allergic effects. Our aim was to investigate the effect of simvastatin on IL-5-induced eosinophil chemotaxis and its regulatory mechanisms.

Separation and quantitation of three acidic herbicide residues in tobacco and soil by dispersive solid-phase extraction and UPLC-MS/MS.

A method for the determination of three acidic herbicides, dicamba, 2,4-dichlorophenoxyacetic acid (2,4-D) and 2,4,5-trichlorophenoxyacetic acid (2,4,5-T) in tobacco and soil has been developed based on the use of liquid-liquid extraction and dispersive solid-phase extraction (dispersive-SPE) followed by UPLC-MS/MS. Two percentage of (v/v) formic acid in acetonitrile as the extraction helped partitioning of analytes into the acetonitrile phase. The extract was then cleaned up by dispersive-SPE using primary secondary amine as selective sorbents.

Indigo naturalis upregulates claudin-1 expression in human keratinocytes and psoriatic lesions.

Ethnopharmacological Relevance: Indigo naturalis is used in traditional Chinese medicine to treat various dermatoses. Our previous clinical studies showed that indigo naturalis is an effective treatment for psoriasis. Herein, the capabilities of indigo naturalis extract and its derivatives to increase claudin-1 expression and tight junction (TJ) function in human keratinocytes and psoriatic lesions were further studied.

Factors associated with purity, biological function, and activation potential of endothelial colony-forming cells.

Endothelial colony-forming cells (ECFCs) are undergoing extensive investigations to tackle certain deliberating cardiovascular diseases. However, the success of this approach depends on a thorough understanding of ECFC biology. This study sought to determine the factors associated with the purity, biological function, and activation potential of ex vivo expanded ECFCs.

[Spatial distribution pattern of soil nitrogen in croplands at county scale and related affecting factors].

By using geostatistics and GIS, this paper studied the spatial distribution of soil nitrogen in the croplands in Shuangliu County of Sichuan Province, China, and analyzed the related affecting factors. There was a moderate spatial correlation between the contents of total nitrogen (TN) and available nitrogen (AN) in the cropland soils, and the spatial correlation distance was 15480 m for TN and 26980 m for AN. The regions with higher soil TN content were mainly in the north of the County, i.

Anti-inflammatory effects of the extract of indigo naturalis in human neutrophils.

Ethnopharmacological Relevance: Indigo naturalis is used by traditional Chinese medicine to treat various inflammatory diseases.

Aim Of The Study: Topical indigo naturalis ointment showed efficacy in treating psoriasis in our previous clinical studies. In this study, we investigated the anti-inflammatory effects of the extract of indigo naturalis (QD) and its main components indirubin, indigo, and tryptanthrin in human neutrophils.

Interleukin-1 receptor antagonist (IL-1RA) prevents apoptosis in ex vivo expansion of human limbal epithelial cells cultivated on human amniotic membrane.

Stem cells of the corneal epithelium have been found to be located exclusively at the anatomical junction between the cornea and the conjunctiva, the limbus. Ex vivo expanded limbal epithelial cells on amniotic membrane (AM) are capable of restoring the corneal surface with limbal stem cell deficiency. Recent studies indicate that intact AM preserves the limbal epithelial phenotype and that distinct epithelial morphology is noted among various culture matrix.