Purpose: This study aims to assess the clinical outcomes of hypofractionated proton beam therapy (PBT) for extrahepatic cholangiocarcinoma (EHCC) and to investigate the optimal sequencing for combining PBT with chemotherapy.
Materials And Methods: We retrospectively analyzed fifty-nine consecutive patients with inoperable EHCC treated with PBT. The median prescribed dose of PBT was 50 GyE (range, 45-66 GyE) in 10 fractions.
We aimed to evaluate the accuracy of the artificial intelligence (AI)-based software INF-M01 in diagnosing suspected bladder tumors using cystoscopy images. Additionally, we aimed to assess the ability of INF-M01 to distinguish and mark suspected bladder cancer using whole cystoscopy images. : A randomized retrospective clinical trial was conducted using a total of 5670 cystoscopic images provided by three institutions, comprising 1890 images each (486 bladder cancer images and 1404 normal images).
View Article and Find Full Text PDFObjectives: Observational studies have reported that diabetes is a risk factor that increases the risk of atherosclerotic cardiovascular disease (ASCVD). However, the causal relationship remains a matter of debate. This study aimed to analyze the relationship between fasting serum glucose (FSG) and ASCVD.
View Article and Find Full Text PDFPurpose: Although South Korea's health insurance has a co-payment-decreasing policy for cancer survivors, information on the extent of financial toxicity and its related factors is limited. We assessed the level of financial toxicity and the association of high levels of financial toxicity with employment concerns after diagnosis and cancer-related distress in working-age cancer survivors.
Materials And Methods: A cross-sectional study was conducted.
Tuberc Respir Dis (Seoul)
December 2024
We study the evolution of conditional mutual information (CMI) in generic open quantum systems, focusing on one-dimensional random circuits with interspersed local noise. Unlike in noiseless circuits, where CMI spreads linearly while being bounded by the light cone, we find that noisy random circuits with an error rate p exhibit superlinear propagation of CMI, which diverges far beyond the light cone at a critical circuit depth t_{c}∝p^{-1}. We demonstrate that the underlying mechanism for such rapid spreading is the combined effect of local noise and a scrambling unitary, which selectively removes short-range correlations while preserving long-range correlations.
View Article and Find Full Text PDFDongchimi, a traditional Korean watery kimchi, relies on complex interactions among diverse lactic acid bacteria (LAB) to maintain its freshness and quality. Recently, dongchimi has gained attention as a health-promoting food due to its content of probiotics and prebiotics. In this study, six probiotic strains were employed into dongchimi fermentation, and its sensory and microbial characteristics were evaluated.
View Article and Find Full Text PDFBackground: This study aimed to develop a clinical model to predict late-onset fetal growth restriction (FGR).
Methods: This retrospective study included seven hospitals and was conducted between January 2009 and December 2020. Two sets of variables from the first trimester until 13 weeks (E1) and the early third trimester until 28 weeks (T1) were used to develop the FGR prediction models using a machine learning algorithm.
Background And Purpose: The immune response following aneurysmal subarachnoid hemorrhage (aSAH) can exacerbate secondary brain injury and impact clinical outcomes. As the immune response after aSAH is a dynamic process, we aim to track and characterize immune cell trajectories over time to identify patterns associated with various clinical outcomes.
Methods: In this retrospective single-center study of patients with aSAH, we analyzed immune cell count trajectories, including neutrophil, monocyte, and lymphocyte counts, collected from day 1 to day 14.
Background: Tangeretin, a natural polymethoxyflavone compound, possesses potent anti-inflammatory activity that improves respiratory inflammation in chronic obstructive pulmonary disease (COPD). However, the molecular mechanisms underlying the anti-COPD effects of tangeretin remain unclear. In this study, we aimed to investigate the key molecular mechanisms by which tangeretin suppresses COPD-related inflammatory responses.
View Article and Find Full Text PDF