Publications by authors named "Su Jin Jo"

The growing threat of antimicrobial resistance (AMR), exacerbated by the COVID-19 pandemic, highlights the urgent need for alternative treatments such as bacteriophage (phage) therapy. Phage therapy offers a targeted approach to combat bacterial infections, particularly those resistant to conventional antibiotics. This study aimed to standardize an agar plate method for high-mix, low-volume phage production, suitable for personalized phage therapy.

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Canine otitis externa, characterized by the involvement of diverse bacterial species, notably Pseudomonas aeruginosa and Staphylococcus pseudintermedius, necessitates antibiotic administration as the primary therapeutic approach; however, prolonged treatment often precipitates antibiotic resistance. Therefore, the application of bacteriophages as antimicrobial agents has been of interest recently. However, phage therapy has limitations; its efficacy depends on the lytic capacity of the phage and the emergence of phage resistance, which can be overcome by using phage cocktails.

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Background: Fire blight, caused by Erwinia amylovora, poses a significant threat to global agriculture, with antibiotic-resistant strains necessitating alternative solutions such as phage therapy. Scaling phage therapy to an industrial level requires efficient mass-production methods, particularly in optimizing the seed culture process. In this study, we investigated large-scale E.

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A female narrow-ridged finless porpoise () stranded on a beach on Jeju Island showed epithelial proliferative skin lesions on its body. Two false killer whales (), caught using nets near Gangneung and Samcheok, respectively, had multiple plaques on their penile epidermis. Histological examination of the epidermis revealed that all the lesions had common features, including accentuated rete pegs, ballooning changes, and eosinophilic intranuclear inclusion (INI) bodies.

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Despite the precarious state of marine turtles as a highly endangered species, our understanding of their diseases remains limited. This case report presents a detailed pathological investigation of spirorchiidiasis, a blood fluke infection that poses a substantial threat to marine turtles. This retrospective study examined three cases of spirorchiid-infected sea turtles, specifically, green sea turtles stranded on Jeju Island, South Korea.

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Erwinia amylovora, the primary causative agent of blight disease in rosaceous plants, poses a significant threat to agricultural yield worldwide, with limited effective countermeasures. The emergence of sustainable alternative agents such as bacteriophages is a promising solution for fire blight that specifically targets Erwinia. In this study, we isolated pEp_SNUABM_01 and pEa_SNUABM_55 from a South Korean apple orchard soil, analyzed their genomic DNA sequences, and performed a comprehensive comparative analysis of Hena1 in four distinct sections.

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Article Synopsis
  • - Human fishing practices pose significant risks to marine ecosystems, threatening coastal cetaceans like dolphins and porpoises through ingestion of fishing gear and bycatch.
  • - A case study on Jeju Island highlighted an Indo-Pacific finless porpoise that ingested fishing hooks and suffered from severe Anisakis infection, illustrating the direct consequences of fishing on marine life.
  • - The study calls for urgent action to mitigate the negative impacts of fishing activities on marine mammals and emphasizes the need for further research on the distribution and health of coastal cetaceans in Korean waters.
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Heat-killed probiotics offer an alternative approach to enhance growth and disease resistance in farmed fish. In this study, we isolated Lactiplantibacillus plantarum VSG3 from the gut of Labeo rohita to investigate the effects of heat-killed L. plantarum (HK-LP) on the health and growth performance of Cyprinus carpio fingerlings.

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Article Synopsis
  • Spinal deformities like kyphoscoliosis are frequently observed in cetaceans, particularly bottlenose dolphins, but information on their occurrence in narrow-ridged finless porpoises (NFP) is scarce.
  • In November 2021, two dead NFPs were found in South Korea, and post-mortem computed tomography (PMCT) revealed they had congenital and degenerative forms of kyphoscoliosis.
  • The study suggests that while kyphoscoliosis may not have directly caused their deaths, it likely limited their spinal movement and mobility, which could have contributed to their demise, marking a significant documentation in understanding NFP health.
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In this case report, we present a rare occurrence of a narrow-ridged finless porpoise (), discovered on the coast of Jeju Island, Republic of Korea, that was afflicted with adhesive bowel obstruction (ABO), a life-threatening condition that has scarcely been reported in cetaceans. Diagnosis of ABO was confirmed via radiological and clinical assessments. Post-mortem computed tomography and necropsy revealed ABO between two loops of the jejunum at the L8 level.

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  • Fire blight is a harmful bacterial disease that affects plants and causes big money problems worldwide.
  • Using antibiotics to fight it has raised concerns about the environment and resistance, so scientists are looking at bacteriophages as another option.
  • This study found that adding certain substances, like polysorbate 80 and kaolin, helps make bacteriophages stronger in sunlight, so they can stick to plants better and last longer.
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Amid the escalating challenges of antibiotic resistance, bacterial infections have emerged as a global threat. Bacteriophages (phages), viral entities capable of selectively infecting bacteria, are gaining momentum as promising alternatives to traditional antibiotics. Their distinctive attributes, including host specificity, inherent self-amplification, and potential synergy with antibiotics, render them compelling candidates.

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This study evaluated the effects of jamun leaf extract (JLE) as a feed supplement on growth performance, haemato-immunological, oxidative stress-related parameters, and cytokine gene expression in Cyprinus carpio challenged with Aeromonas hydrophila.. Diets containing four different JLE concentrations, that is, 0 (basal diet), 5 (JLE5), 10 (JLE10), and 15 g kg (JLE15), were fed to carp (6.

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The recent outbreak of blight in pome fruit plants has been a major concern as there are two indistinguishable species, and , which cause blight in South Korea. Although there is a strict management protocol consisting of antibiotic-based prevention, the area and the number of cases of outbreaks have increased. In this study, we isolated four bacteriophages, pEp_SNUABM_03, 04, 11, and 12, that infect both and and evaluated their potential as antimicrobial agents for administration against -originated blight in South Korea.

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This study evaluated the effects of Bougainvillea glabra (BG) leaf as a feed supplement on growth, skin mucosal immune parameters, serum oxidative stress, expression of immune-related genes, and susceptibility to pathogen infection in carp Cyprinus carpio. Diets containing four different BG concentrations (g kg), i.e.

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Recently, there has been an increasing number of blight disease reports associated with and in South Korea. Current management protocols that have been conducted with antibiotics have faced resistance problems and the outbreak has not decreased. Because of this concern, the present study aimed to provide an alternative method to control the invasive fire blight outbreak in the nation using bacteriophages (phages) in combination with an antibiotic agent (kasugamycin).

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With concern growing over antibiotics resistance, the use of bacteriophages to combat resistant bacteria has been suggested as an alternative strategy with which to enable the selective control of targeted pathogens. One major challenge that restrains the therapeutic application of bacteriophages as antibacterial agents is their short lifespan, which limits their antibacterial effect in vivo. Here, we developed a polylactic-co-glycolic acid (PLGA)/alginate-composite microsphere for increasing the lifespan of bacteriophages in vivo.

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Natural products have gained considerable attention for improving fish growth performance and immunity to enhance disease resistance. This study evaluated the effect of dandelion polysaccharides (DP) on skin mucosal immune parameters, immune-related gene expression, and susceptibility to pathogen challenge in the Common carp Cyprinus carpio. Diets containing four different concentrations of DP (g Kg):0 g [basal diet], 0.

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In the aquaculture industry, an efficient and safe water purification system is important to prevent mass mortality by virulent pathogens. As extensive use of traditional methods (e.g.

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Extended-spectrum β-lactamases (ESBLs), particularly those of the CTX-M types, are the predominant resistance determinants of Escherichia coli that are rapidly spreading worldwide. To determine CTX-M types, E. coli isolates were collected from retail chickens (n = 390) and environmental samples from chicken farms (n = 32) and slaughterhouses (n = 67) in Korea.

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Article Synopsis
  • Beta-casein is an important protein found in the milk of most mammals.
  • Scientists looked at specific parts of the gene that makes this protein in pigs and found out how it gets turned on by certain signals.
  • They discovered that for the gene to work properly, two key areas in the gene (one part near the beginning and a second part called intron 1) are needed for the production of beta-casein in pig cells.
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