Publications by authors named "Su Jian"

Ginseng Radix et Rhizoma and its preparations are often adulterated with Panacis Quinquefolii Radix. Based on the research on Ginseng Radix et Rhizoma and Panacis Quinquefolii Radix, the causes and analytical method of adulteration were determined. A UPLC-MS/MS method was developed for the detection of Panacis Quinquefolii Radix mixed in Ginseng Radix et Rhizoma, with pseudoginsenoside F_(11) as the marker.

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The plants of Rutaceae, with wide distribution in China, have a long history of medicinal use. They contain a wide variety of alkaloids, which include isoquinolines, quinolines, acridones, carbazoles, and indoles. Pharmacological studies have shown that most of these alkaloids have antitumor, anti-inflammatory, antiviral, antidiabetic and other activities.

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The growing threat of electromagnetic pollution has become a pressing safety concern. Metal-organic framework (MOF) derivatives are considered ideal candidates for mitigating electromagnetic radiation. However, due to the limitations imposed by complex post-processing and disruption of pristine crystal structures, the mechanisms of electromagnetic wave absorption remain unclear, let alone achieving atomic-level regulation in MOF derivatives.

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Background: Birth weight has been reported to be associated with chronic obstructive pulmonary disease (COPD) in adulthood, but the results have not yet been determined. This study aims to analyse the potential association of birth weight with COPD risk in UK Biobank.

Methods: We conducted a prospective analysis for participants without baseline COPD in UK Biobank.

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The measurement of human breathing is crucial for assessing the condition of the body. It opens up possibilities for various intelligent applications, like advanced medical monitoring and sleep analysis. Conventional approaches relying on wearable devices tend to be expensive and inconvenient for users.

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  • * Results showed that a higher PRS was more strongly related to EGFR-positive LUAD cases (OR=8.63) than to EGFR-negative cases (OR=3.50), indicating a significant association based on mutation status.
  • * These findings imply that genetic susceptibility to LUAD differs in never-smoking East Asian women depending on whether the cancer has specific mutations, which could affect public health strategies and clinical practices.*
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The Jiangsu Biobank for the Prevention and Control of Diabetes (JBPCD) is a community-based prospective cohort study initiated in Jiangsu province, to examine the burden of complications associated with type 2 diabetes mellitus (T2DM). This study aims to better understand the incidence, risk factors, and long-term outcomes of T2DM complications to inform prevention and control strategies. From October 2013 to July 2014, 20,053 T2DM patients (7,862 males and 12,191 females) were recruited from Suzhou city and Huai'an city.

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A novel aptamer LFA (Apt-LFA) strip is first constructed for ethyl carbamate (EC) detection, in which cationic polyethyleneimine (PEI) and anionic polyacrylamide (APAM) are used as double-capture agents. The black NiCoO nanoparticles (NCO NPs) encapsulated by EC1-34 aptamer are employed as recognition probes. The added EC will bind to EC1-34 aptamer on the probes, so that the test-line (T-line) immobilized with APAM can electrostatically capture the exposed NCO NPs.

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The Eel Virus European X (EVEX) is a significant pathogen contributing to the decline of eel populations. As an important evolutionary driving force, it is crucial to understand whether homologous recombination (HR)occurs between EVEXs for revealing the evolutionary patterns of the virus. This study indicates that HR may enhance genetic diversity and accelerate the evolution and spread of EVEX.

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  • Efficient and low-cost hydrogen evolution catalysts are vital for water electrolysis, and this study presents a method for creating MoN catalysts on nickel foam to improve performance.
  • The catalyst's effectiveness is influenced by nitrogen sources and nitridation temperatures, with a specific configuration showing high activity due to its unique spindle-like nanosheet structure.
  • The adjusted chemical environment from N doping enhances the catalyst's properties, demonstrating superior hydrogen evolution performance with promising metrics like low overpotential and fast reaction kinetics, positioning MoN as a strong alternative to expensive catalysts like platinum.
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Background: The fracture of bone plate can cause considerable pain for the patient and increase the burden on the public finances. This study aims to explore the failure mechanism of 49 plates retrieved from revision surgery and introduce pure magnesium (Mg) block to improve the biomechanical performance of the plate via decreasing the stiffness and to stimulate the biological response of the plate potentially by the degradation of Mg block.

Methods: The morphological analysis and component analysis of the plates were conducted to determine the fracture reason of the plates combining the clinical data.

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A novel approach, to the best of our knowledge, for generating short microwave pulse trains based on a hybrid mode-locked optoelectronic oscillator (HML-OEO) is proposed and demonstrated. In the proposed scheme, a saturable absorber (SA) device is inserted into the active mode-locked OEO (AML-OEO) to compress the pulse width of the microwave pulse trains. Numerical simulations and experimental results show that the HML-OEO generates a short microwave pulse train with a repetition rate of 98.

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Background: Acetaminophen (APAP)-induced hepatotoxicity is a major cause of acute liver failure (ALF), during which autophagy is triggered as a cellular defense mechanism. Shaoyao-Gancao Decoction (SGD), a traditional prescription in Chinese Medicine, is renowned for its therapeutic effects on liver diseases. However, the efficacy and mechanisms of SGD in treating APAP-induced liver injury remain underexplored.

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The rational design of porous covalent organic frameworks (COFs) with high conductivity and reversible redox activity is the key to improving their performance in sodium-ion batteries (SIBs). Herein, we report a series of COFs (FPDC-TPA-COF, FPDC-TPB-COF, and FPDC-TPT-COF) based on an organosulfur linker, (trioxocyclohexane-triylidene)tris(dithiole-diylylidene))hexabenzaldehyde (FPDC). These COFs feature two-dimensional crystalline structures, high porosity, good conductivity, and densely packed redox-active sites, making them suitable for energy storage devices.

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Regulation of the two-photon excited fluorescence (TPEF) emission intensity and wavelength of metal-organic framework (MOF) crystals with similar constitutions presents a significant challenge. In this study, two MOFs, Zn-BTPPA and Cd-BTPPA, were constructed using tetrakis(1,1'-biphenyl-4-carboxylic acid)-1,4-benzenediamine (HBTPPA) as the organic ligand and mononuclear Zn and trinuclear Cd inorganic nodes, respectively. The incorporation of HBTPPA within the MOF structures enables effective TPEF emission in both Zn-BTPPA and Cd-BTPPA.

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  • The Taiwanese Dermatological Association and Taiwan Lung Cancer Society made new guidelines for doctors to help patients with skin problems caused by cancer medicine.
  • These guidelines explain the reasons why some cancer treatments can cause skin issues and share advice from skin specialists in Taiwan.
  • Most doctors agreed on these recommendations, which will help them treat patients with skin problems resulting from lung cancer treatments more effectively.
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  • - Integrated donor-acceptor photothermal units and specific catalytic sites into a metal-organic framework.
  • - Created a system that leverages photothermal effects for enhanced catalytic activity.
  • - Achieved efficient conversion of carbon monoxide (CO) into cyclic carbonates using this advanced framework.
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Objective: The purpose of this study is to compare the wear properties of UHMWPE acetabular liners after undergoing 3 million (3 Mc) and 5 million (5 Mc) cycles of wear testing. The results will serve as a reference for the design of testing for hip prostheses and as a control for clinical revision removals.

Methods: Wear tests were conducted on three different sizes of acetabular liners (28 mm, 32 mm, and 36 mm internal diameters) using a hip simulator to determine the amount of wear after 3 and 5 million cycles.

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The classification of critical physiological signals using neuromorphic devices is essential for early disease detection. Physical reservoir computing (RC), a lightweight temporal processing neural network, offers a promising solution for low-power, resource-constrained hardware. Although solution-processed memcapacitive reservoirs have the potential to improve power efficiency as a result of their ultralow static power consumption, further advancements in synaptic tunability and reservoir states are imperative to enhance the capabilities of RC systems.

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Objective: Socioeconomic status (SES) has been proven to be associated with chronic obstructive pulmonary disease (COPD) in Western populations, but the evidence is very limited in China. This study aimed to investigate the association between SES and the risk of COPD incident.

Methods: This study was based on the China Kadoorie Biobank (CKB) project in Wuzhong District, Suzhou.

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Background: Detecting event triggers in biomedical texts, which contain domain knowledge and context-dependent terms, is more challenging than in general-domain texts. Most state-of-the-art models rely mainly on external resources such as linguistic tools and knowledge bases to improve system performance. However, they lack effective mechanisms to obtain semantic clues from label specification and sentence context.

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Background: The rising prevalence of Type 2 diabetes (T2D) in China poses a critical health challenge, necessitating effective management strategies. The National Essential Public Health Services Program (NEPHSP), initiated in 2009, focuses on equitable access to health services, including T2D management. This study investigates the associations between perceived care quality, self-care behaviors, and glycemic control in Chinese adults with T2D under NEPHSP, particularly examining the mediating role of self-care behaviors.

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The electrocatalytic nitrate reduction reaction (NITRR) holds great promise for purifying wastewater and producing valuable ammonia (NH). However, the lack of efficient electrocatalysts has impeded the achievement of highly selective NH synthesis from the NITRR. In this study, we report the design and synthesis of two polynuclear Co-cluster-based coordination polymers, {[Co(TCPPDA)(HO)]·(HO)(DMF)} and {Co(TCPPDA)[(CH)NH]·(HO)(DMF)} (namely, and ), which possess distinct coordination motifs with well-defined porosity, high-density catalytic sites, accessible mass transfer channels, and nanoconfined chemical environments.

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A stable lithium metal-organic framework, constructed using a redox-active ,,','-tetrakis(4-carboxyphenyl)-1,4-phenylenediamine linker and Li cluster-based one-dimensional rod secondary building unit, exhibits good stability and reversible redox activity. The Li-MOF, which can be oxidized by AgNO, has the potential to function as an electrochromic device, thereby advancing the development of smart MOF materials.

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  • * The newly developed multi-ancestry PRS showed a strong correlation with LUAD risk, indicating that individuals in the highest PRS percentile had significantly increased risk compared to those in the lowest.
  • * Findings suggest that those in the highest risk category have a lifetime risk of about 6.69%, and they reach the average population's 10-year risk for LUAD by age 41, highlighting the importance of multi-ancestry PRS for better risk assessment in this group.
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