Metastatic conjunctival squamous cell carcinoma presenting as infectious sclerokeratouveitis.

Purpose: We describe a case of metastatic conjunctival squamous cell carcinoma (SCC) presenting as an infectious sclerokeratouveitis in a patient with autoimmune disease.

Observations: A 63-year-old Caucasian female presented to the cornea service with a raised perilimbal scleral infiltrate, hypopyon, and corneal perforation concerning for infectious necrotizing sclerokeratoveitis. She had an ocular history of a recurrent "pyogenic granuloma" and her medical history was notable for well-controlled systemic lupus erythematosus and rheumatoid arthritis.

Prospective cohort study investigating frequency and risk factors for acute pain 1 day after refractive surgery.

Background/aims: To examine demographic and clinical factors associated with ocular pain 1 day after refractive surgery.

Methods: Prospective study of individuals undergoing refractive surgery. Participants rated their ocular pain on a 0-10 numerical rating scale (NRS) presurgery and 1 day after surgery.

Landolt Ring-Shaped Epithelial Keratopathy: A Novel Corneal Disease in a Non-Japanese White Patient.

Purpose: Landolt ring-shaped epithelial keratopathy is a corneal disease that has only been reported in 11 Japanese patients in 2014. 1 We describe the first case of Landolt ring-shaped epithelial keratopathy in the United States in a patient of European background.

Methods: This is a single case report with longitudinal care.

Ocular Pain after Refractive Surgery: Interim Analysis of Frequency and Risk Factors.

Purpose: To examine the frequency and risk factors for ocular pain after laser assisted in situ keratomileusis (LASIK) and photorefractive keratectomy (PRK).

Design: Prospective study of individuals undergoing refractive surgery at 2 different centers.

Participants: One hundred nine individuals undergoing refractive surgery: 87% LASIK and 13% PRK.

Experimental design considerations for studies of human tear proteins.

Purpose: Human tears contain abundant, diverse sets of proteins that may serve as biomarkers of ocular surface health. There is a need for reproducible methods that consider multiple factors influencing the tear proteome, in addition to the variable of interest. Here we examined a workflow for proteomic analysis of tear proteins without the need to pool tear samples from multiple individuals, thus allowing for analyses based on individual factors, and increasing opportunities for protein biomarker discovery.

Human MPox (Monkeypox) Virus Membranous Keratoconjunctivitis With Transient Corneal Hypoesthesia and Late Symblepharon Formation: A Novel Case and Clinical Implications.

Purpose: The aim of this study was to describe a case of corneal involvement as an early manifestation of ocular disease in the 2022 human mpox (monkeypox) virus outbreak.

Methods: This is a single case report with longitudinal care.

Results: A 47-year-old immunocompetent man presented with viral conjunctivitis before development of skin lesions or systemic symptoms.

Early Complications With Preloaded Descemet Membrane Endothelial Keratoplasty Are Not Dependent on Optisol-GS Washout or Trypan Blue Restaining.

Purpose: To describe the intraoperative and early postoperative complications using preloaded Descemet membrane endothelial keratoplasty (DMEK) grafts with intraocular injection of the graft in Optisol-GS and omission of trypan blue restaining.

Methods: This is a retrospective case series of 132 consecutive eyes with Fuchs endothelial dystrophy or endothelial failure who underwent DMEK using preloaded donor tissue prepared as previously described. The graft was not restained with trypan blue by the surgeon, and Optisol-GS was injected with the graft into the eye instead of being rinsed from the injector.

Contrast Sensitivity After Wavefront-Guided and Wavefront-Optimized PRK and LASIK for Myopia and Myopic Astigmatism.

Purpose: To compare contrast sensitivity among participants undergoing wavefront-guided or wavefront-optimized photorefractive keratectomy (PRK) or LASIK for the treatment of myopia or myopic astigmatism 12 months after surgery.

Methods: In a prospective, randomized clinical trial, 215 participants with myopia ranging from -0.50 to -7.

Corneal and Corneoscleral Injury in Combat Ocular Trauma from Operations Iraqi Freedom and Enduring Freedom.

Objectives: To examine the incidence and the etiology of corneal and corneoscleral injuries in the setting of combat ocular trauma, and to determine what effect these injuries have on overall visual impairment from combat ocular trauma.

Methods: Retrospective, noncomparative, interventional case series, analyzing U.S.

Wavefront-Guided Versus Wavefront-Optimized Photorefractive Keratectomy: Visual and Military Task Performance.

Purpose: To compare visual performance, marksmanship performance, and threshold target identification following wavefront-guided (WFG) versus wavefront-optimized (WFO) photorefractive keratectomy (PRK).

Methods: In this prospective, randomized clinical trial, active duty U.S.

Goblet cell response after photorefractive keratectomy and laser in situ keratomileusis.

Purpose: To determine whether patients without dry eye preoperatively have an altered conjunctival goblet cell density and mucin secretion postoperatively and to explore what factors affect changes in goblet cell density and mucin secretion.

Setting: The former Walter Reed Army Medical Center, Washington, DC, USA.

Design: Prospective nonrandomized clinical study.

Sutureless cryopreserved amniotic membrane graft and wound healing after photorefractive keratectomy.

Purpose: To evaluate the effect of sutureless cryopreserved amniotic membrane (Prokera) on corneal wound healing after photorefractive keratectomy (PRK).

Setting: Center for Refractive Surgery, Walter Reed Army Medical Center, Washington, DC, USA.

Design: Prospective nonrandomized control trial.

Wavefront-optimized surface retreatments of refractive error following previous laser refractive surgery: a retrospective study.

Background: Retreatments are sometimes necessary to correct residual or induced refractive errors following refractive surgery. Many different combinations of primary treatment methods and retreatment techniques have been studied, however, few studies have investigated wavefront-optimized (WFO) technology for retreatment following primary refractive surgery. This study aimed to report the outcomes of WFO photorefractive keratectomy (PRK) retreatments of refractive error following previous laser refractive surgery with PRK, laser in situ keratomileusis (LASIK), or laser-assisted subepithelial keratectomy (LASEK).

Wavefront-guided versus wavefront-optimized photorefractive keratectomy: Clinical outcomes and patient satisfaction.

Purpose: To compare visual outcomes following Visx Star S4 Customvue wavefront-guided and Allegretto Wave Eye-Q 400 Hz wavefront-optimized photorefractive keratectomy (PRK).

Setting: Warfighter Refractive Eye Surgery Program and Research Center, Fort Belvoir, Virginia, and Walter Reed National Military Medical Center, Bethesda, Maryland, USA.

Design: Prospective randomized clinical trial.

Traumatic cataracts secondary to combat ocular trauma.

Purpose: To describe the characteristics, visual outcomes, and predictive value of the Ocular Trauma Score (OTS) in eyes with traumatic cataract from combat ocular trauma.

Setting: Walter Reed Army Medical Center, Washington, DC, USA.

Design: Retrospective case series.

The U.S. Army Surface Ablation Study: comparison of PRK, MMC-PRK, and LASEK in moderate to high myopia.

Purpose: To compare visual outcomes following photorefractive keratectomy (PRK), PRK with mitomycin C (MMC-PRK), and LASEK in moderate and high myopia in military personnel.

Methods: This prospective, randomized contralateral eye study included 167 patients 21 years or older with manifest spherical equivalent -5.99 ± 1.

Anterior segment imaging in combat ocular trauma.

Purpose. To evaluate the use of ocular imaging to enhance management and diagnosis of war-related anterior segment ocular injuries. Methods.

Residency training in refractive surgery.

Purpose: To evaluate resident refractive surgery caseload and surgical outcomes in an academic medical center.

Setting: Walter Reed Army Medical Center, Washington, DC, USA.

Design: Comparative case study.

Alcohol versus brush PRK: visual outcomes and adverse effects.

Background And Objective: A smooth corneal surface prior to laser ablation is important in order to achieve a favorable refractive outcome. In this study, we compare PRK outcomes following two commonly used methods of epithelial debridement: Amoils epithelial scrubber (brush) versus 20% ethanol (alcohol).

Study Design/patients And Methods: We reviewed records of patients who underwent wavefront-optimized PRK for myopia or myopic astigmatism between January 2008 and June 2010.

Visual and IOP outcomes after PRK in pigment dispersion syndrome.

Purpose: To report the results of photorefractive keratectomy (PRK) in patients with pigment dispersion syndrome.

Methods: The pre- and postoperative records of patients with pigment dispersion syndrome who underwent PRK between January 2002 and March 2009 were reviewed. Data for analysis included gender, age, ablation depth, surgical complications, manifest refraction spherical equivalent, uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), intraocular pressure (IOP), central corneal thickness (CCT), cup-to-disc (c/d) ratio, and postoperative complications.

Photorefractive keratectomy in posterior polymorphous dystrophy with vesicular and band subtypes.

Purpose: To evaluate the safety and efficacy of photorefractive keratectomy (PRK) in patients with posterior polymorphous dystrophy (PPMD) with vesicular and band subtypes.

Setting: Walter Reed Center for Refractive Surgery, Washington, DC, USA.

Design: Case series.

Effect of blast trauma and corneal foreign bodies on visual performance.

Purpose: To evaluate the effect of non-penetrating corneal foreign bodies secondary to explosive blasts on the visual performance of soldiers.

Methods: In a prospective, non-interventional study subjective visual performance and objective optical quality of 11 injured eyes with retained corneal foreign bodies were compared with that of 11 normal controls. Visual performance measures consisted of best spectacle-corrected high-contrast visual acuity (HCVA), low-contrast (5%) visual acuity (LCVA), and contrast sensitivity (CS).

Effect of brimonidine tartrate 0.15% on night-vision difficulty and contrast testing after refractive surgery.

Purpose: To evaluate the efficacy of brimonidine tartrate ophthalmic solution 0.15% in patients with night-vision difficulties after laser refractive surgery.

Setting: Center for Refractive Surgery, Walter Reed Army Medical Center, Washington, District of Columbia, USA.

Effects of lotrafilcon A and omafilcon A bandage contact lenses on visual outcomes after photorefractive keratectomy.

Purpose: To evaluate postoperative healing between bandage contact lenses with high and low oxygen permeability in patients having photorefractive keratectomy (PRK).

Setting: Center for Refractive Surgery, Walter Reed Army Medical Center, Washington, DC, USA.

Methods: This retrospective study compared patients receiving a high-oxygen-transmission bandage contact lens (Focus Night & Day [N&D], Ciba Vision; n = 92) and those receiving a low-oxygen-transmission lens (Proclear, Cooper Vision; n = 114) after PRK.