Can diffusion-weighted imaging serve as a biomarker of fibrosis in pancreatic adenocarcinoma?

Purpose: To assess the relationship between diffusion-weighted imaging (DWI) and intravoxel incoherent motion (IVIM)-derived quantitative parameters (apparent diffusion coefficient [ADC], perfusion fraction [f], D , diffusion coefficient [D], and D , pseudodiffusion coefficient [D*]) and histopathology in pancreatic adenocarcinoma (PAC).

Materials And Methods: Subjects with suspected surgically resectable PAC were prospectively enrolled in this Health Insurance Portability and Accountability Act (HIPAA)-compliant, Institutional Review Board-approved study. Imaging was performed at 1.