Publications by authors named "Stuart Kelly"

Mask mandates for children were implemented at schools and childcare centers during the COVID-19 pandemic, and the US continues to recommend masking down to the age of two in certain settings. Medical interventions should be informed by high-quality evidence and consider the possibility of harm (i.e.

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Background: Mask mandates for children during the COVID-19 pandemic varied in different locations. A risk-benefit analysis of this intervention has not yet been performed. In this study, we performed a systematic review to assess research on the effectiveness of mask wearing in children.

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Article Synopsis
  • The introduction emphasizes the need for an in vitro model to detect adverse drug reactions affecting microvascular function and vascular tone.
  • The PM-1, a new automated perfusion myograph, enables researchers to test the effects of drugs on blood vessels by controlling pressure and flow while also measuring vascular permeability.
  • Results showed that Ivermectin enhanced flow-mediated dilatation and thrombin increased vessel permeability, demonstrating the PM-1's effectiveness in drug testing for potential vascular responses.
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Computational fluid dynamics (CFD) analysis can provide detailed, three-dimensional predictions of blood flow through mechanical heart valves, which can help to optimize valve hemodynamics and reduce the potential for blood clotting. A number of CFD studies, considering both forward and retrograde flow through valves, have been published. In this paper, a geometrically accurate CFD model capable of predicting the three-dimensional, time-dependent flow through an open ATS bileaflet valve is presented.

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