Targeted free energy estimation via learned mappings.

Free energy perturbation (FEP) was proposed by Zwanzig [J. Chem. Phys.

Quantification and significance of fluid shear stress field in biaxial cell stretching device.

A widely used commercially available system for the investigation of mechanosensitivity applies a biaxial strain field to cells cultured on a compliant silicone substrate membrane stretched over a central post. As well as intended substrate strain, this device also provides a fluid flow environment for the cultured cells. In order to interpret the relevance of experiments using this device to the in vivo and clinical situation, it is essential to characterise both substrate and fluid environments.

Scanning electrochemical microscopy: approach curves for sphere-cap scanning electrochemical microscopy tips.

The parameters of functions used to predict diffusion-controlled scanning electrochemical microscopy approach curves under positive and negative (hindered diffusion) feedback for sphere-cap tips are reported. These functions were obtained by fitting approach curves simulated with an error-bounded adaptive finite element algorithm. Several geometries corresponding to different sphere-cap dimensions were considered including the effect of the tip insulating sheath.