[Stereotactic radiotherapy of spinal hemangioblastoma].

Hemangioblastoma (HAB) is a benign, richly vascularized tumor that accounts for 2-6% of all spinal cord neoplasms and ranks third in the structure of intramedullary space-occupying lesions of the spinal cord. Hemangioblastoma may occur sporadically or, in approximately 30% of cases, as part of the clinical picture of a hereditary disease, von Hippel-Lindau disease. The aim of this study was to evaluate the efficacy and safety of stereotactic irradiation of hemangioblastomas of the spinal localization in patients with sporadic and von Hippel-Lindau-associated hemangioblastomas The results of stereotactic radiotherapy were evaluation of 210 spinal hemangioblastomas in 74 patients.

Thromboelastometry-Based Prophylaxis for Venous Thromboembolism in the Acute Period Following Isolated Severe Traumatic Brain Injury.

Objective: Traumatic brain injury (TBI) is an independent risk factor for venous thromboembolism (VTE). This study aimed to determine the optimal timing for initiating pharmacological thromboprophylaxis for VTE in patients with isolated severe TBI using rotational thromboelastometry (ROTEM).

Methods: This single-center observational study enrolled 115 patients aged 18-59 years with isolated severe TBI within the first 48 hours after injury.

[Minimally invasive surgical treatment of extramedullary tumors at the level of craniovertebral junction: experience of the Burdenko Neurosurgical Center].

Objective: To describe own experience of treating patients with extramedullary tumors at the level of craniovertebral junction using minimally invasive surgical approaches.

Material And Methods: The study included 29 patients who underwent minimally invasive microsurgical resection of extramedullary tumors at the level of craniovertebral junction. We analyzed the main clinical and surgical parameters.

Quantitative analysis of orbit volume and eyeball position after resection of hyperostotic sphenoid wing meningioma and simultaneous orbital wall reconstruction using individual technologies.

Objective: To conduct a quantitative analysis of orbit volume at different stages of preparation and surgical treatment of patients with cranio-orbital meningiomas undergoing resection with simultaneous orbital wall reconstruction using 3D modeling and 3D printing technologies.

Material And Methods: A prospective cohort non-randomized study included 24 patients with cranio-orbital meningiomas. The volumes were measured by segmenting the orbital structures using the planimetric method in the Inobitec PRO software package.

Reconstruction of orbital walls after resection of cranioorbital meningiomas: a systematic review and meta-analysis of individual patient data.

Following meningioma removal, there are numerous methods available for reconstructing the orbital wall. This systematic review seeks to summarize the published data on the surgical treatment of cranioorbital meningiomas, and to analyze the effectiveness and safety of various techniques and materials used for the reconstruction of bony orbital walls. We conducted a search of the two databases and included original articles with a series of 10 or more cases.

Comparison of methods of treatment of meningiomas invading the superior sagittal sinus.

Unlabelled: There are various approaches to the treatment of patients with parasagittal meningiomas.

Objective: To optimize treatment strategy for meningiomas invading the superior sagittal sinus.

Material And Methods: The study included 87 patients with benign parasagittal meningiomas between 2010 and 2012.

Intraoperative Neurophysiologic Monitoring in Predicting Dysphagia After Brainstem and Fourth Ventricle Surgery.

Objective: Dysphagia represents the main complication of posterior fossa neurosurgery. Adequate diagnosis of this complication is warranted to prevent untimely extubation with subsequent aspiration. Intraoperative neurophysiologic monitoring (IONM) modalities may be used for this purpose.

Data Quality Estimation Via Model Performance: Machine Learning as a Validation Tool.

In our recent study, the attempt to classify neurosurgical operative reports into routinely used expert-derived classes exhibited an F-score not exceeding 0.74. This study aimed to test how improving the classifier (target variable) affected the short text classification with deep learning on real-world data.

Pulmonary embolism in neurosurgical patients.

Unlabelled: Pulmonary embolism (PE) is a serious problem for neurosurgical patients because of high risk of mortality and the need to choose effective and safe anticoagulation.

Objective: To analyze the patients with PE after neurosurgical interventions.

Material And Methods: A prospective study was performed at the Burdenko Neurosurgical Center between January 2021 and December 2022.

Decompression fusion surgery and minimally invasive microsurgical decompression in patients with single-segment lumbar spinal stenosis.

Unlabelled: There are few studies comparing clinical efficacy of decompression/fusion surgery (transforaminal lumbar interbody fusion (TLIF) + transpedicular interbody fusion) and minimally invasive microsurgical decompression (MMD) in patients with single-segment lumbar spinal stenosis.

Objective: To compare the results of TLIF + transpedicular interbody fusion and MMD in patients with single-segment lumbar spinal stenosis.

Material And Methods: A retrospective observational cohort study included medical records of 196 patients (100 (51%) men, 96 (49%) women).

Infectious complications in acute period after traumatic brain injury.

Unlabelled: Patients with traumatic brain injury (TBI) are at high risk of infection.

Objective: To delineate infections in acute period of TBI, association between intracranial lesion type and risk of infection, as well as to estimate treatment outcomes in these patients depending on infection.

Material And Methods: This study included 104 patients with TBI (80 men and 24 women) aged 33.

Surgical and combined treatment of patients with craniovertebral junction meningioma: a single-center retrospective study of 196 cases.

Unlabelled: Treatment of craniovertebral junction meningioma is a difficult task. Surgical treatment is the gold standard for these patients. However, it is associated with high risk of neurological impairment, while combined treatment (surgery + radiotherapy) provides more favorable outcomes.

Autologous fibrin glue for endoscopic skull base repair in patients with cerebrospinal fluid leakage.

Unlabelled: The main stages of endoscopic skull base repair in patients with cerebrospinal fluid (CSF) leakage are identification of bone boundaries of the fistula and its closure by auto- and allografts. Fibrin glue can be used to fix plastic materials and additionally seal skull base defect.

Objective: To analyze efficacy and safety of Vivostat autologous fibrin glue for endoscopic skull base repair in patients with nasal CSF leakage and to compare postoperative outcomes after defect closure by Vivostat fibrin glue and allogeneic fibrin glue.

Minimally invasive microsurgical decompression in patients with monosegmental lumbar spinal stenosis.

Unlabelled: Surgical treatment of degenerative lumbar spinal stenosis is an actual problem of modern spinal surgery and orthopedics.

Objective: To analyze the results of minimally invasive microsurgical decompression (MI-MD) in patients with monosegmental lumbar spinal stenosis.

Material And Methods: A retrospective observational cohort study was performed.

Role of TERT mutation for treatment prognosis in patients with IDH-negative anaplastic astrocytoma.

Objective: To study the effect of mutation on overall and relapse-free survival in patients with -negative diffuse astrocytomas grade III (anaplastic gliomas).

Material And Methods: The study included 45 patients aged 45.5 years.

Predicting the Length of Stay in Neurosurgery with RuGPT-3 Language Model.

In this study, we update the evaluation of the Russian GPT3 model presented in our previous paper in predicting the length of stay (LOS) in neurosurgery. We aimed to assess the performance the Russian GPT-3 (ruGPT-3) language model in LOS prediction using narrative medical records in neurosurgery compared to doctors' and patients' expectations. Doctors appeared to have the most realistic LOS expectations (MAE = 2.

Multinomial Classification of Neurosurgical Operations Using Gradient Boosting and Deep Learning Algorithms.

This study aimed at testing the feasibility of neurosurgical procedures classification into 100+ classes using natural language processing and machine learning. A catboost algorithm and bidirectional recurrent neural network with a gated recurrent unit showed almost the same accuracy of ∼81%, with suggestions of correct class in top 2-3 scored classes up to 98.9%.

Surgical Treatment of Large and Giant Anterior Cerebral Artery Aneurysms in the Endovascular Era: Analysis of Large Clinical Series.

Objective: Analysis of results of surgical treatment of 112 patients with large and giant anterior cerebral artery (ACA) aneurysms.

Methods: This is the largest clinical series of large and giant ACA aneurysms ever reported. Retrospective analysis of medical charts, radiographic studies, and intraoperative videos was performed.

[Anaplastic pleomorphic xanthoastrocytoma - single-center analysis of 42 patients].

Unlabelled: Anaplastic pleomorphic xanthoastrocytoma is a rare tumor. There are still no objective data on the incidence of its diagnosis.

Objective: To study neuroimaging, morphological features of tumors, as well as factors affecting treatment and prognosis.

Length of Stay Prediction in Neurosurgery with Russian GPT-3 Language Model Compared to Human Expectations.

Patients, relatives, doctors, and healthcare providers anticipate the evidence-based length of stay (LOS) prediction in neurosurgery. This study aimed to assess the quality of LOS prediction with the GPT3 language model upon the narrative medical records in neurosurgery comparing to doctors' and patients' expectations. We found no significant difference (p = 0.

A Comparison of Word Embeddings to Study Complications in Neurosurgery.

Our study aimed to compare the capability of different word embeddings to capture the semantic similarity of clinical concepts related to complications in neurosurgery at the level of medical experts. Eighty-four sets of word embeddings (based on Word2vec, GloVe, FastText, PMI, and BERT algorithms) were benchmarked in a clustering task. FastText model showed the best close to the medical expertise capability to group medical terms by their meaning (adjusted Rand index = 0.

Hippocampal Dosimetry and Mnemonic Function Changes After Stereotactic Irradiation of Cavernous Sinus Meningiomas.

Introduction: It is believed that hippocampal exposure plays a major role in the development of memory disorders after cranial irradiation. This effect is evident in whole-brain irradiation and is less certain in local irradiation of intracranial targets. The present study aims to clarify the dosimetric features and dynamics of memory functions after local irradiation of the hippocampus when treating cavernous sinus meningiomas.