Neoangiogenesis is involved in the development and progression of malignant tumors. Vascular endothelial growth factor (VEGF) and its receptors have been designated a central part in this process. Since the significance of the assessment of angiogenesis in soft tissue tumors is still a matter of debate, we investigated the vascularisation of cardiac myxomas and compared it with pulmonary artery sarcomas (PAS).
View Article and Find Full Text PDFAnnu Int Conf IEEE Eng Med Biol Soc
March 2008
This paper presents a full proteomics analysis LC-MS (Liquid Chromatography-Mass Spectrometry) chain combining bio, nano and information technologies in order to quantify targeted proteins in blood sample. The objective is to enable an early detection of pancreatic cancer. We focus on the data processing step which estimates the proteins' concentration.
View Article and Find Full Text PDFAnnu Int Conf IEEE Eng Med Biol Soc
March 2008
There is a need to precisely measure concentration of proteins in biological substance for early diagnosis of disease or knowledge of fundamental biological processes. Many apparatus have been proposed, and now data processing methods have to be investigated. This paper focuses on data processing of proteomic experiments combining nano liquid chromatography and mass spectrometry.
View Article and Find Full Text PDFObjectives: Due to an increase in the percentage of older people in industrialized countries there is an increasing demand for medical care for the elderly. With advancing age, a series of structural, architectural and compositional modifications take place in the vasculature. Therefore, we analyzed the influence of patient age on the reocclusion rate of recanalized peripheral arteries.
View Article and Find Full Text PDFIntra-arterial application of dissolved tablets is associated with a high risk of tissue necrosis. An early active vasodilatating and recanalising treatment is necessary. We present the case of 21-year-old female who applied three dissolved Flunitrazepam tablets into the ulnar artery and was successfully treated with prostaglandin E1 and recombinant tissue plasminogen activator.
View Article and Find Full Text PDFPurpose: To evaluate any correlation of fibrinogen and hematocrit with the early success of balloon angioplasty for peripheral arterial occlusive disease (PAOD) and compare the outcomes of angioplasty in diabetic and nondiabetic patients.
Methods: From November 1997 through October 2000, 330 patients (246 men; mean age 63.6+/-10.
Resulting from phase-analytical and chemical examinations there are characteristically habitual differences in the consistency of dental calculus. Very obvious are sex (gender) specific and job specific differences concerning the contents of heavy metals like lead, cadmium, copper, and zinc. Characteristics concerning the quantity, consistency and temper of dental calculus as well as the peal-homogeneous value (pH-value) of the saliva are obvious with miners working in salt-mines.
View Article and Find Full Text PDFSalivary calculi consist of a concentrically arranged, heterogeneous mixture of different phosphates of calcium, together with an inorganic matrix. The different crystalline phases are: hydroxyl- and carbonate-apatite, whitlockite and calcium octaphosphate. Investigation of 50 cases of sialothiasis (salivary gland disease) revealed characteristic sex-dependent differences in the uptake of toxic heavy metals by salivary calculi.
View Article and Find Full Text PDFA method is described for the analysis of chromium in saliva by atomic absorption spectrometry. Cr was determined by using the Zeeman background correction, and with optimization of all the conditions of the Stabilized Temperature Platform Furnace (STPF). The low detection limit and the ability to analyse very small sample volumes make this technique especially suitable for epidemiological surveys.
View Article and Find Full Text PDFThe efficiency of extremely small particles of hydroxylapatite on a therapy with hypersensitive tooth-necks was approved in a double-blind-study. 90% of the test persons stated an improvement of their complaints after 3-5 days, and 50% became complaintless within the time of study. The manner of working was proved with the help of x-ray inclination and by polarisation-optical studies.
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