Extreme events in frequency-swept semiconductor lasers.

We analyze a delay differential equation model for a frequency-swept semiconductor laser and demonstrate existence of extreme events in its dynamics, with probabilities heavily dependent on the sweep rate. The extreme events appear even in absence of any noise in the system and do not exhibit significant dependence on its presence. We investigate the problem numerically and show that intensity dynamics of these events are highly localized in the filter detuning space.

Dissipative Kerr soliton generation at 2μm in a silicon nitride microresonator.

Chip-scale optical frequency combs enable the generation of highly-coherent pulsed light at gigahertz-level repetition rates, with potential technological impact ranging from telecommunications to sensing and spectroscopy. In combination with techniques such as dual-comb spectroscopy, their utilization would be particularly beneficial for sensing of molecular species in the mid-infrared spectrum, in an integrated fashion. However, few demonstrations of direct microcomb generation within this spectral region have been showcased so far.

Functional Activity of Blood Neutrophils in Patients with Stable Course and Exacerbation of Chronic Obstructive Pulmonary Disease.

We performed a comparative study of the parameters of chemiluminescence of blood neutrophils in patients with different severity of chronic obstructive pulmonary disease in its different periods. The maximum values of induced and spontaneous chemiluminescence were recorded at moderate severity of the disease during exacerbation. Low levels of chemiluminescence indicators were found in severe chronic obstructive pulmonary disease in the stable phase.

Hybrid integrated SiN external cavity laser with high power and narrow linewidth.

We have designed and fabricated a hybrid integrated laser source with full C-band wavelength tunability and high-power output. The external cavity laser is composed of a gain chip and a dual micro-ring narrowband filter integrated on the silicon nitride photonic chip to achieve a wavelength tuning range of 55 nm and a SMSR higher than 50 dB. Through the integration of the semiconductor optical amplifier in the miniaturized package, the laser exhibits an output power of 220 mW and linewidth narrower than 8 kHz over the full C-band.

Tunable photo-induced second-harmonic generation in a mode-engineered silicon nitride microresonator.

All-optical poling enables reconfigurable and efficient quasi-phase-matching for second-order parametric frequency conversion in silicon nitride integrated photonics. Here, we report broadly tunable milliwatt-level second-harmonic generation in a small free spectral range silicon nitride microresonator, where the pump and its second-harmonic are both always on the fundamental mode. By carefully engineering the light coupling region between the bus and microresonator, we simultaneously achieve critical coupling of the pump as well as efficient extraction of second-harmonic light from the cavity.

Subharmonic locking and frequency combs in frequency-swept semiconductor lasers.

We analyze a delay differential equation model for a swept semiconductor laser and demonstrate existence of various periodic solutions that are subharmonically locked to the sweep rate. These solutions provide optical frequency combs in spectral domain. We investigate the problem numerically and show that, due to the translational symmetry of the model, there exists a hysteresis loop formed by branches of steady states solutions, bridges of periodic solutions connecting stable and unstable steady state branches, and isolated branches of limit cycles.

[Safety and efficacy of a new method of percutaneous nephrolithotripsy performed under ultrasound and endovisual control without the use of intraoperative x-ray examination].

Purpose Of The Study: to study the safety and efficacy of using a new method of performing percutaneous nephrolithotripsy under ultrasound and endovisual control.

Materials And Methods: A comparative analysis of the results of percutaneous nephrolithotripsy performed under ultrasound and endovisual control in 515 (84.1%) patients (main group) and percutaneous nephrolithotripsy performed under fluoroscopic control in 97 (15.

Volatile Organic Compound Fragmentation in the Afterglow of Pulsed Glow Discharge in Ambient Air.

Glow discharge (GD) source gained an increased level of attention in relation to the analysis of volatile organic compounds (VOCs) since past work showed that this soft ionization method allowed direct analysis of VOCs with minimal fragmentation, however, the issue of fragmentation was not previously studied in detail. The aim of the present work was to investigate the effect of discharge conditions on VOC fragmentation in the system consisting of the cell with pulsed glow discharge and a time-of-flight mass spectrometer. Ionization of VOCs of different classes (hydrocarbons, alcohols, esters, and carboxylic acids) was investigated.

Linear Electro-optic Effect in Silicon Nitride Waveguides Enabled by Electric-Field Poling.

Stoichiometric silicon nitride (SiN) is one of the most mature integrated photonic platforms for linear and nonlinear optical applications on-chip. However, because it is a centrosymmetric material, second-order nonlinear processes are inherently not available in SiN, limiting its use for multiple classical and quantum applications. In this work, we implement thermally assisted electric-field poling, which allows charge carrier separation in the waveguide core, leading to a depletion zone formation and the inscription of a strong electric field reaching 20 V/μm.

Near perfect two-photon interference out of a down-converter on a silicon photonic chip.

Integrated entangled photon-pair sources are key elements for enabling large-scale quantum photonic solutions and address the challenges of both scaling-up and stability. Here we report the first demonstration of an energy-time entangled photon-pair source based on spontaneous parametric down-conversion in silicon-based platform-stoichiometric silicon nitride (SiN)-through an optically induced second-order (χ) nonlinearity, ensuring type-0 quasi-phase-matching of fundamental harmonic and its second-harmonic inside the waveguide. The developed source shows a coincidence-to-accidental ratio of 1635 for 8 µW pump power.

Relationship of Nutritional Status and Spirometric Parameters in Children with Bronchial Asthma.

Unlabelled: The potential mechanisms of bronchial asthma (BA) negative modification under the influence of obesity are currently being actively studied. However, at present, the effect of nutritional status on bronchial obstruction in children with BA cannot be considered established. In this regard, the was to study the relationship of spirometric parameters reflecting bronchial patency with nutritional status in children with asthma.

Anatomy of the digestive system of lumpfish (Cyclopterus lumpus) as an adaptation to puffing behavior.

The first description of the histology of the digestive tract of the lumpfish Cyclopterus lumpus showed an adaptation for collecting and storing water. The morphology of this species' tract is mostly typical of carnivorous fishes, having a sac-like stomach for storage and a relatively short intestine of approximately 1.2× the standard body length.

Highly tunable second-harmonic generation in all-optically poled silicon nitride waveguides.

The availability of nonlinear parametric processes, such as frequency conversion in photonic integrated circuits is essential. In this contribution, we demonstrate a highly tunable second-harmonic generation in a fully complementary metal-oxide-semiconductor (CMOS)-fabrication-compatible silicon nitride integrated photonic platform. We induce the second-order nonlinearity using an all-optical poling technique with the second-harmonic light generated in the fundamental mode, and a narrow quasi-phase matching (QPM) spectrum by avoiding higher-order mode mixing.

[The rehabilitation of patients with acute polymorphic psychotic disorder].

Aim: To assess the effectiveness of a rehabilitation program in patients with acute polymorphic psychotic disorder.

Material And Methods: The study included 128 patients in remission. The rehabilitation program was administered to 75 patients with acute polymorphic psychotic disorder.

Visible blue-to-red 10 GHz frequency comb via on-chip triple-sum-frequency generation.

A broadband visible (VIS) blue-to-red, 10 GHz repetition rate frequency comb is generated by combined spectral broadening and triple-sum-frequency generation in an on-chip silicon nitride waveguide. Ultra-short pulses of 150 pJ pulse energy, generated via electro-optic modulation of a 1560 nm continuous-wave laser (CW), are coupled to a silicon nitride waveguide giving rise to a broadband near-infrared (NIR) supercontinuum. Modal phase matching inside the waveguide allows direct triple-sum-frequency transfer of the NIR supercontinuum into the VIS wavelength range covering more than 250 THz from below 400 to above 600 nm wavelength.

[The development of Altai psychiatric service (The 60-th anniversary of Psychiatry Department of the Altai State Medical University)].

The article describes a short history of psychiatry in Altai since 1941. Active efforts of local psychiatrists, in particular the leaders and staff of the psychiatry department of the Altai state medical university, have led to the great progress in this field.

Waveguide-PAINT offers an open platform for large field-of-view super-resolution imaging.

Super-resolution microscopies based on the localization of single molecules have been widely adopted due to their demonstrated performance and their accessibility resulting from open software and simple hardware. The PAINT method for localization microscopy offers improved resolution over photoswitching methods, since it is less prone to sparse sampling of structures and provides higher localization precision. Here, we show that waveguides enable increased throughput and data quality for PAINT, by generating a highly uniform ~100 × 2000 µm area evanescent field for TIRF illumination.

[Microbiological analysis as effective tool for optimization of empirical antibiotic therapy in the urological clinic].

Aim: to study the features of microbiota in patients of urological departments and to optimize the schemes of antibiotic therapy.

Materials And Methods: Data of microbiological studies in patients of urological departments in 2017 years were analyzed. Isolation of pathogens was carried out using standard techniques.

[Genetic variations in Clupea pallasii herring from okhotsk sea based on microsatellite markers].

The genetic variations among spawning groups of herrings from different spawning grounds of the northwestern part of the Okhotsk Sea was assessed using ten microsatellite loci. All loci were polymorphic with the ex- pected heterozygosity estimates varying at different loci in the range of 0.7-95.

[Formation of genetic diversity in populations of Pacific cod (Gadus macrocephalus Tilesius) (Gadidae)].

The variability of the Gmo3, Gmo34, Gmo35, Pgmo32, Gmo19 microsatellite DNA loci was examined in the population samples of Pacific cod from different parts of the North Pacific. The statistical tests showed that the differentiation of the population was the result of different levels of reproductive autonomy of the individual Pacific cod populations, formed in the Pleistocene-Holocene period with the specific features of transgressions and regressions of the World Ocean, and supported by the existing system of currents and the features of the migratory behavior of cod in the North Pacific.

[Comparative analysis of genetic variability of White Sea Cod (Gadus morhua marisalbi) at allozyme and microsatellite markers].

Variability of cod spawning and feeding schools from Kandalaksha Bay of the White Sea, was examined at six allozyme and eight microsatellite loci. The degree of genetic differentiation at allozyme loci constituted 0 = 0.36% [95% bootstrap interval 0.

[Analysis of microsatellite loci variations in herring (Clupea pallasii marisalbi) from the White Sea].

The genetic diversity among spawning groups of herring from different parts of the White Sea was assessed using ten microsatellite loci. All loci were polymorphic with the expected heterozygosity estimates varying in the range of 12.7-94.

[On differentiation of cod (Gadus morhua L.) groups in Baltic Sea].

Using the AGP*, PGI-1*, PGI-2*, LDH*, IDH*, and PGM* allozyme markers, the differentiation of cod groups during the spawning period in Baltic Sea was evaluated. It was shown that cod samples from the eastern and western parts of Baltic Sea (being statistically significantly different from the cod samples from the Norwegian Sea, Barents Sea, and the Skagerrak Strait) demonstrated a high degree of identity (I = 0.99-1.

[Preliminary data on variation of four microsatellite loci in Pacific herring Clupea pallasii].

Variation of microsatellite loci Cpa 10, Cpa 113, Cpa4, and Cpa7 was for the first time examined in Pacific-type herring Clupea pallasii from the White Sea (CI. pallasii marisalbi), the Kara Sea (CI. pallasii suworowi), the Sea of Okhotsk, and Lake Nerpich'e, Kamchatka Bay, northwestern Pacific (CI.