Neonatal Meningitis Due to .

is a new emerging foodborne bacterial pathogen associated with fatal infections such as meningitis, necrotizing enterocolitis, and septicemia in neonates. Powdered infant formula milk has been recognized as one of the main transmission vehicles and contaminated sources of this pathogen. Educating parents about the importance of hygienic reconstitution of powdered infant formula, storage practices, and hand hygiene is crucial to reducing the risk of this life-threatening infection.

Whole-Spine MRI in Children With Suspected Abusive Head Trauma.

Abusive head trauma (AHT) in children has recently been associated with findings on cervical spine MRI. The purpose of this study was to evaluate whether whole-spine MRI in children with suspected AHT shows additional abnormalities not identified on cervical spine MRI. This retrospective study included 256 children younger than 3 years old (170 boys, 86 girls; mean age, 5.

Enteric Distribution of Oral Contrast in Emergency Department Patients Undergoing Abdominal-Pelvic Computed Tomography.

Purpose: The study sought to assess the gastrointestinal (GI) distribution of oral contrast (OC) among emergency department (ED) patients and determine if contrast reaches the terminal ileum or site of pathology to assist in diagnosis.

Methods: Retrospectively, adults undergoing abdominal-pelvic computed tomography (APCT) in the ED at 2 hospitals were identified over a 3-month period. APCTs were reviewed for location of OC.

Signaling pathways involved in megakaryocyte-mediated proliferation of osteoblast lineage cells.

Recent studies suggest that megakaryocytes (MKs) may play a significant role in skeletal homeostasis, as evident by the occurrence of osteosclerosis in multiple MK related diseases (Lennert et al., 1975; Thiele et al., 1999; Chagraoui et al.

Impact of maturational status on the ability of osteoblasts to enhance the hematopoietic function of stem and progenitor cells.

Osteoblasts (OBs) exert a prominent regulatory effect on hematopoietic stem cells (HSCs). We evaluated the difference in hematopoietic expansion and function in response to co-culture with OBs at various stages of development. Murine calvarial OBs were seeded directly (fresh) or cultured for 1, 2, or 3 weeks prior to seeding with 1000 Lin-Sca1 + cKit+ (LSK) cells for 1 week.

Osteoblast lineage cells expressing high levels of Runx2 enhance hematopoietic progenitor cell proliferation and function.

Although osteoblasts (OB) play a key role in the hematopoietic stem cell (HSC) niche, little is known as to which specific OB lineage cells are critical for the enhancement of stem and progenitor cell function. Unlike hematopoietic cells, OB cell surface phenotypic definitions are not well developed. Therefore, to determine which OB lineage cells are most important for hematopoietic progenitor cell (HPC) function, we characterized OB differentiation by gene expression and OB function, and determined whether associations existed between OB and HPC properties.

Melatonin induces Cry1 expression in the pars tuberalis of the rat.

In mammals, interacting transcriptional/post-translational feedback loops involving 'clock genes' and their protein products control circadian organisation. These genes are not only expressed in the master circadian clock of the suprachiasmatic nuclei (SCN) but also in many peripheral tissues where they exhibit similar but not identical dynamic to that seen in the SCN. Among these peripheral tissues, the pars tuberalis (PT) of the pituitary expresses clock genes.

MT1 melatonin receptor mRNA tissular localization by PCR amplification.

Objectives: The pineal gland transduces photoperiodic informations to the neuroendocrine axis through the nocturnally melatonin secretion. This hormonal message plays a major role in the biological rhythm regulation. By autoradiography, more than 130 melatonin putative targets have been reported in the central nervous system (CNS) and in peripheral tissues.

[Does posterior internuclear ophthalmoplegia exist? A report on eleven cases and the results of oculography (author's transl)].

Based on the anatomical and clinical findings in the very rare cases reported, recent experimental data, and the results of oculography, the authors consider that this condition merits definition as an individual entity. It is usually associated with other disorders of oculomotility which may mask clinical signs, and oculography is necessary to establish the diagnosis. Terminologically, it would appear logical to retain the terms; abduction internuclear ophthalmoplegia (and not, posterior), and adduction internuclear ophthalmoplegia (and not, anterior).

[Autoradiography, in the electron microscope, of endocrine pancreatic cells of a teleost fish, Xiphophorus helleri H].

After using the autoradiographic technique in electron microscopy, we were able to verify that there is no adrenergic innervation in the pancreatic islet of Xiphophorus: nerve fibers and nerve endings do not incorporate tritiated noradrenaline. On the other hand, nerve fibers outside the islet, in the mesenteron or in the exocrine pancreas, are labelled.