Publications by authors named "Stoove M"

Background: During the COVID-19 pandemic, governments worldwide introduced law enforcement measures to deter and punish breaches of emergency public health orders. For example, in Victoria, Australia, discretionary fines of A$1,652 were issued for breaching stay-at-home orders, and A$4,957 fines for 'unlawful gatherings'; to date, approximately 30,000 fines remain outstanding or not paid in full. Studies globally have revealed how the expansion of policing powers produced significant collateral damage for marginalized populations, including people from low-income neighboorhoods, Indigenous Peoples, sex workers, and people from culturally diverse backgrounds.

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Background: We aimed to identify motivators for people who inject drugs to pursue treatment for hepatitis C virus (HCV) infection and uncover opportunities that could make treatment more appealing.

Methods: Between November 2023 and January 2024, we conducted semi-structured interviews with 15 HCV RNA-positive individuals with a history of injecting drug use and self-reported as either untreated or treated but delayed treatment for more than 6 months. Thematic and framework data analysis was employed and interpreted using the Capability, Opportunity and Motivation (COM-B) framework of behaviour change.

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Article Synopsis
  • The study focuses on tailored interventions to address the harms of sexualised drug use (SDU) among men who have sex with men (MSM) in Jakarta, Indonesia, considering local risks and cultural factors.
  • Through qualitative interviews with 20 MSM, the research identifies enabling forces from within MSM networks and disabling forces from societal stigma, which create tension in their SDU practices.
  • To effectively mitigate risks associated with SDU, interventions should leverage peer networks and virtual spaces, enhancing their reach and acceptance.
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Background: Needle exchange programs are effective public health interventions that reduce blood-borne infections, including hepatitis C, and injection-related infections. We sought to assess the return on investment of existing Prison Needle Exchange Programs (PNEPs) in Canadian federal prisons and their expansion to all 43 institutions.

Methods: We developed a stochastic compartmental model that estimated hepatitis C and injection-related infections under different PNEP scenarios in Canadian federal prisons.

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Objectives: Whilst public health measures were effective in reducing COVID-19 transmission, unintended negative consequences may have occurred. This study aims to assess changes alcohol consumption and the heavy episodic drinking (HED) during the pandemic.

Methods: Data were from the Optimise Study, a longitudinal cohort of Australian adults September 2020-August 2022 that over-sampled priority populations at higher risk of contracting COVID-19, developing severe COVID-19 or experiencing adverse consequences of lockdowns.

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  • The study examines factors influencing the completion of alcohol and other drug (AOD) treatment, focusing on both demographic and service-level aspects among a large cohort in New South Wales, Australia.
  • It found that around 69.8% of participants completed treatment at least once, with differences in completion rates based on the type of substance, treatment modality, and referral source.
  • Specifically, amphetamine treatments had the lowest completion rates, while mandated treatments through criminal justice agencies and certain AOD modalities, like involuntary treatments, showed significantly higher completion rates.
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  • The study highlights the growing trend of prescribing testosterone for gender affirming hormone therapy (GAHT) in Australia, primarily conducted by general practitioners (GPs), as detailed in AusPATH guidelines.
  • A cross-sectional study named PUSH! Audit was conducted in 9 GP clinics across 5 cities, comparing GAHT patients with cisgender men receiving testosterone for deficiency.
  • Results indicated that GAHT patients were generally younger, had notable health concerns like smoking and anxiety, but showed high monitoring levels and low adverse effects, making GAHT effective in general practice.
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  • The study analyzed the effectiveness of subsidised HIV pre-exposure prophylaxis (PrEP) in Australia from April 2018 to March 2023, focusing on HIV incidence among users over a 5-year period.
  • A total of 66,206 people were included in the study, with an overall HIV incidence rate of 1.07 per 1000 person-years, indicating that higher adherence to PrEP substantially reduced the risk of HIV acquisition.
  • Key factors influencing HIV acquisition included previous treatment for hepatitis C, younger age (18-29), and attending prescribers in areas with lower prevalence of gay men.
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Background: Reversing declining rates of people initiating and completing hepatitis C (HCV) treatment, observed in many countries, is needed to achieve global HCV elimination goals. Providing financial incentives to increase HCV testing and treatment uptake among people at-risk of or living with HCV infection could be an effective intervention. We conducted a systematic review to assess evidence regarding the effectiveness of financial incentives to improve engagement and progression through the HCV care cascade.

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  • Prisons in Victoria, Australia, have implemented a statewide nurse-led model of care since 2015 to enhance hepatitis C testing and treatment among inmates, crucial for elimination efforts.
  • From 2015 to 2021, 3,133 DAA treatment courses were prescribed to 2,768 inmates, with a significant increase in prescriptions over the years and a median age of treated individuals being 39.
  • The program achieved a 93% success rate in sustained viral response (SVR12), demonstrating the effectiveness of decentralized, nurse-led initiatives in tackling hepatitis C in high-prevalence settings like prisons.
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Background: Gay and bisexual men (GBM) remain overrepresented among syphilis diagnoses in Australia and globally. The extent to which changes in sexual networks associated with HIV pre-exposure prophylaxis (PrEP) and treatment as prevention (TasP) may have influenced syphilis transmission among GBM at the population-level is poorly understood. We describe trends in syphilis testing and incidence among GBM in Australia over eleven years spanning widespread uptake of HIV PrEP and TasP.

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Background: Prison needle exchange programs (PNEPs) are a critical component for harm reduction in prisons. Little is known about the PNEP access barriers for people who are incarcerated, but the low uptake in the Canadian program highlights these constraints. We aimed to identify the barriers and potential solutions for increasing PNEP coverage in the nine Canadian federal prisons where they operate.

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Background: Elimination of bloodborne viruses including HIV and hepatitis C virus from prisons requires high coverage of evidence-based interventions that prevent bloodborne virus transmission, including needle and syringe programs. Canada launched a Prison Needle Exchange Program (PNEP) in nine federal prisons in 2018; however, uptake among people who inject drugs in prison remains low. We aimed to explore barriers and facilitators to improving PNEP uptake identified by correctional officers and healthcare workers.

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  • A pilot study in Victoria, Australia, tested the Department of Health's ability to follow up on chronic hepatitis C cases through diagnosing clinicians to improve patient care and data completeness.
  • Out of 513 cases contacted between September 2021 and March 2022, data was successfully collected for 356 cases, with 86.2% of those receiving follow-up care.
  • Challenges included incomplete contact information and difficulty in reaching clinicians, suggesting that improving system automation could enhance notifications and support better patient linkage to care.
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Hepatitis C is a global public health threat, affecting 56 million people worldwide. The World Health Organization has committed to eliminating hepatitis C by 2030. Although new treatments have revolutionised the treatment and care of people with hepatitis C, treatment uptake has slowed in recent years, drawing attention to the need for innovative approaches to reach elimination targets.

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Introduction: To ascertain the adverse health outcomes experienced by those using prescribed testosterone and non-prescribed anabolic-androgenic steroids presenting to general practitioner (GP) clinics.

Methods: Retrospective clinical audit from nine GP clinics in major metropolitan areas across three Australian states. Data included demographic and individual characteristics (age, sexuality, body mass index, smoking status and HIV status); performance and image-enhancing drug use (type, reasons for use, patient-reported adverse effects); and blood biochemistry measurements (lipid profiles, liver function tests and red blood cell tests).

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Mandatory drug testing is commonly used in Australian prisons to detect and deter drug use. In this commentary, we review the limited evidence for mandatory drug testing programs, highlight potential harms associated with their implementation and provide recommendations for drug surveillance in prisons concordant with a harm minimisation framework.

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Introduction: Despite universal access to government-funded direct-acting antivirals (DAAs) in 2016, the rate of hepatitis C treatment uptake in Australia has declined substantially. Most hepatitis C is related to injecting drug use; reducing the hepatitis C burden among people who inject drugs (PWID) is, therefore, paramount to reach hepatitis C elimination targets. Increasing DAA uptake by PWID is important for interrupting transmission and reducing incidence, as well as reducing morbidity and mortality and improving quality of life of PWID and meeting Australia's hepatitis C elimination targets.

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Objective: To identify groups more likely to be referred for HIV testing because of symptomatic presentation rather than as part of asymptomatic screening.

Design: A retrospective analysis of Australian National HIV Registry (NHR) surveillance data including sociodemographic and clinical data, as well as reasons for HIV test.

Methods: Using notification records from 2017 to 2022, we summarised reasons for testing leading to an HIV diagnosis.

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  • A study evaluated a hepatitis C care model in Cairns, Australia, which integrated financial incentives to enhance patient engagement in testing and treatment for those with a history of injecting drugs.
  • Between March 2020 and May 2021, clients received AUD 20 for participating in various stages of hepatitis C care, leading to significant improvements in treatment initiation, completion, and sustained virological response compared to standard care practices.
  • Results showed that financial incentives led to a higher percentage of participants beginning (86% vs. 75%), completing (75% vs. 40%), and achieving sustained viral response (68% vs. 17%) in comparison to the previous 11 months without incentives.
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Background: Achieving virtual elimination of HIV transmission in Australia requires a combination of high treatment rates and high testing coverage among individuals at risk of acquiring HIV. HIV self-testing (HIVST) is an additional testing approach for key populations.

Objective: We aimed to examine the knowledge, attitudes, and practices of HIVST among Asian-born gay, bisexual and other men who have sex with men (GBMSM).

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Background: In Australia, the incidence of hepatitis C virus (HCV) has declined among gay and bisexual men (GBM) with human immunodeficiency virus (HIV) since 2015 and is low among GBM using HIV preexposure prophylaxis (PrEP). However, ongoing HCV testing and treatment remains necessary to sustain this. To assess the potential utility of sexually transmissible infections (STIs) to inform HCV testing among GBM with HIV and GBM using PrEP, we examined the association between bacterial STI diagnoses and subsequent primary HCV infection.

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To reach World Health Organization elimination targets for hepatitis C, different strategies are needed to reach people who have not yet been diagnosed and treated. In the context of declining treatment initiation rates, innovation in service design and delivery is necessary: testing and treatment needs to be offered to people in non-traditional settings. The community corrections (probation and parole) population is larger than the prison population, which has high prevalence of hepatitis C and-in some countries-established diagnosis and treatment programs.

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