[Radiocardiographic assessment of the effect of digoxin on heart conduction insufficiency].

On 29 patients with heart insufficiency radiocardiographical investigations in rest and under stress were carried out before and after treatment with digoxin. Here it was shown that in existing functional insufficiency the determination of the stroke volume and of the minute volume in rest after digitalisation did not result in a remarkable change, but in obstructive insufficiency an improvement of the pump function of the heart began already under conditions of rest. Only in stress also in patients with functional insufficiency a significant increase of the heart-time volume and the stroke volume after application of glycoside was proved.

[Isotope nephrographic studies during hormonal contraception using Depositon].

By means of isotope nephrograms of a total of 29 renally healthy women who had been taken for more than 1 year the drug Deposiston, the renal function is investigated. Checking is done by using the semiquantitative evaluation parameters according to Zum Winkel, Pabst and Hör and to own criteria. Our results show that the highly dosed application of estrogens does not induce significant changes of renal function in the isotope nephrogram.

["Hypothyroid" goitre in puberty treated with a combined T3/T4 preparation (author's transl)].

After administration of combined T3/T4 preparations (ratio of 4 : 1) to juveniles with goitre, size II-III (WHO), and hypothyroid T4 or PBI levels, the T3 value reached hyperthyroid levels 7-8 hours afterwards. The increased T3 level with normal T4 blood levels can lead to iatrogenic T3 hyperthyroidism. Serial tests demonstrated that at increasing doses a raised T3/T4 ratio, which is observed with low T4 values, can return to normal but with increasing doses this ratio, caused by T3 rise, can again become elevated.

[Performance of uteroplacental perfusion in contrast to hormone-analytic investigations in intrauterine retardation and under the influence of intravenous long-term application of heparin (author's transl)].

The digital estimation of utero-placental circulation by means of nuclear-medical examinations with help of 113 m In-Cl and regarding to the "region of interest" gives no depositions in cases with an intrauterine retardation. This concerns the activity as well in the placenta as in the uterus too. Exceptions represents intrauterine retardations on the base of heaviness EPH-gestosis and placenta previa.

[Sequential scintigraphy in the investigation of changes in renal function during pregnancy (author's transl)].

Changes in renal function during pregnancy were studied by sequential scintigraphy in 16 women with normal kidneys. The examinations were carried out during the first and third trimesters. Time activity curves were obtained by a computer-assisted storage and analysis procedure, using a "region of interest" technique for renal parenchyma and renal pelvis.

[TRH refractory TSH values, triiodothyronine levels and T3/T4 quotients in hypothyroid children treated with T3/T4 preparations (author's transl)].

TRH-tests, triiodothyronine (T3), TBI, and thyroxine (T4) determinations were carried out in 23 children with primary hypothyroidism treated with T3/T4-preparations. T3/T4 quotients were calculated. 7 out of 10 patients with TRH refractory TSH values and normal T4 levels had T3 values above normal range.

["Prophylactic" intrathecal radiogold (198au) in leukaemia in children (author's transl)].

198Au radiogold-colloid (Behring) was injected as "prophylactic" therapy against central nervous system leukaemia in 26 children with acute leukaemia (22 acute lymphatic and 4 myeloid). During the period of observation (1.3.

[Comparison of 2 isotope-nephrography-evaluation methods in normal pregnancy].

The isotope nephrograms of a total of 31 renally healthy pregnant women of different thirds of pregnancy are semiquantitatively investigated by 2 methods. The results are demonstrated graphically. This comparison show that a more correct result can be made with the describing method by taking a greater number of parameters describing the excretory phase.

[Intracranial arteriovenous malformation in one family -- oto- and neurological aspects (author's transl)].

Intracranial arteriovenous malformations in a father and daughter are described. The pathology involved in one of the patients was localized in the left dura, whereas that of the other was located in the left parietal lobe. Although clinical symptoms were different in each patient, possible hereditary factors in causing the malformations are discussed.

[The dyspnea syndrome of the newborn in Switzerland. Results of a cooperative study within the framework of the Swiss Neonatology Group].

The Swiss Neonatology Group was founded in 1972 to strengthen cooperation between obstetricians and pediatricians in this country. To this end a collaborative study was made of the incidence of respiratory distress syndrom in Switzerland during 1974. Almost every neonatal unit of the country participated, and the study thus covered the problem cases taken from approximately 90% of all Swiss newborns.

Arteriovenous malformations of the transverse dural sinus.

Clinical, radioanatomical, and therapeutic aspects of dural arteriovenous malformations in the region of the transverse sinsu are discussed on the basis of seven personal observations and the analysis of 72 reported cases. Common symptoms are headache and troublesome tinnitus aurium. More serious neurological deficiencies may occur as a result of distrubance in cerebral hemodynamics.

[Periodontal conditions of the teeth next to the fracture line after stable plate osteosynthesis in the mandible].

Follow-ups in 21 patients with 30 fractures of the lower jaw which were treated with stable plate osteosynthesis showed that 94% of the teeth adjacent to the fracture line were not extracted. The rate of secondary healing was 7%. Evaluation of the periodontal conditions showed that only 14% of the teeth were not worth keeping and 45% of the teeth required treatment.

[A comparison of isotope nephrographic examinations during pregnancy and hormonal contraception (author's transl)].

Renal function was investigated by isotope nephrography in 31 pregnant women with normal kidneys during various phases of pregnancy, and in 137 women on continuous contraceptive steroids (up to eight years). The semi-quantitative parameters of zum Winkel were used. It was found that the use of oral contraceptives did not lead to any change in renal function, whereas with advancing pregnancy there was distinct excretion delay on the isotope nephrogram.