Publications by authors named "Sting L Shi"
Article Synopsis
- Vitamin B deficiency can cause serious issues like neurological damage and anemia, and is linked to chronic diseases, yet current tests for it are not very reliable.
- Researchers used metabolomic profiling to analyze serum samples from individuals with low vitamin B levels and identified 77 metabolites, which revealed significant differences in certain compounds between control and deficient groups.
- They determined that the ratio of taurine to chenodeoxycholic acid could serve as a strong biomarker for predicting low vitamin B levels, supported by mouse model studies showing significant metabolic changes due to deficiency.
Aging is associated with changes in circulating levels of various molecules, some of which remain undefined. We find that concentrations of circulating taurine decline with aging in mice, monkeys, and humans. A reversal of this decline through taurine supplementation increased the health span (the period of healthy living) and life span in mice and health span in monkeys.
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