Proliferating cell nuclear antigen (PCNA) as a prognostic factor for colorectal cancer.

PCNA (proliferating cell nuclear antigen) is a cell cycle related protein that is maximally elevated in late G1 and S-phase of proliferating cells. 114 biopsy specimens of colorectal cancer were immunolabeled with PC 10 which specifically recognizes PCNA; Dukes' staging and histological grading were estimated for each case. All patients were followed-up for at least 60 months or to death.

Biomechanical features of axial injuries to the lower limbs and to the pelvic ring by motor car collisions.

By frontal car collision, passengers are exposed, commonly, by dynamic deceleration force, applied to the lower limb and acting in the direction of the femoral shaft axis. This force could be transmitted from the foot, or from the knee to the hip joint, resulting in typical fractures of the femoral shaft, upper part of the femur as of the acetabulum. The authors have described radiological feature and three dimensional definition of these fractures as well as their ergonomic characteristics.