Publications by authors named "Stijn Chris Arnold Robijns"
Article Synopsis
- A screening was carried out on a small-molecule library to find inhibitors that prevent and eliminate Salmonella biofilms across various temperatures, while avoiding effects on bacterial growth to reduce resistance development.
- Out of 20,014 compounds screened, 140 were identified as potential inhibitors, leading to further testing of their effectiveness at temperatures of 16, 25, 30, and 37 °C.
- One notable compound, 7-methoxy-4-[4-(3-phenyl-2-propen-1-yl)-1-piperazinyl]-5H-pyrimido[5,4-b]indole, showed promise in preventing biofilm formation, with an analogue, 8-fluoro-4-[4