Regional cartilage properties of three quadruped tibiofemoral joints used in musculoskeletal research studies.

Quadruped joints are commonly used in musculoskeletal studies as a surrogate for human joints despite inherent differences in tissue properties. Although concerns exist regarding model validity, relatively few studies comparing the mechanical properties of quadruped tissue exist. This study aimed to characterise the regional intrinsic mechanical properties and thickness of tibiofemoral cartilage from three quadrupeds used in modern musculoskeletal research.

The effect of bone fragment size and cerebrospinal fluid on spinal cord deformation during trauma: an ex vivo study.

Object: The purpose of the study was to assess the effect of CSF and the size of the impacting bone fragment area on spinal cord deformation during trauma.

Methods: A transverse impact rig was used to produce repeated impacts on bovine and surrogate cord models. Tests were recorded with high-speed video and performed on specimens with and without CSF and/or dura mater and with 3 different impactor areas.