Publications by authors named "Stewart Pine"
Article Synopsis
- Sarcopenia, a condition characterized by loss of muscle mass, is prevalent in end-stage liver disease and can worsen patient outcomes during liver transplantation (LT).
- This study assessed the practicality of using MRI to analyze body composition in LT patients, tracking changes both while on the waiting list and after transplantation.
- Results indicated that a majority of participants had high muscle fat infiltration and low muscle volume at waitlisting, but after LT, there were increases in muscle volume and fat distribution, suggesting potential benefits from early intervention and monitoring.
Unlabelled: Chronic kidney disease (CKD) is associated with cardiovascular (CV) events, a leading complication in liver transplant recipients (LTRs). Timely subspecialty care is associated with improved clinical outcomes in patients with CKD. This study sought to assess associations between nephrology comanagement and CV events among LTRs at risk for or with CKD.
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- Some medical treatments for rare conditions, like liver transplants, don't always have specific studies to guide doctors, so they often rely on expert opinions for better care.
- A new method called © helps create these guidance recommendations by combining existing guidelines, expert agreement, and understanding the challenges doctors face in following them.
- This approach includes input from everyone involved, like patients and caregivers, to ensure the recommendations are helpful and can be put into practice more easily.
Transjugular intrahepatic portosystemic shunt (TIPS) is an effective intervention for portal hypertensive complications, but its effect on renal function is not well characterized. Here we describe renal function and characteristics associated with renal dysfunction at 30 days post-TIPS. Adults with cirrhosis who underwent TIPS at 9 hospitals in the United States from 2010 to 2015 were included.
View Article and Find Full Text PDFData for liver transplant recipients (LTRs) regarding the benefit of care concordant with clinical practice guidelines for management of blood pressure (BP) are sparse. This paper reports on clinician adherence with BP clinical practice guideline recommendations and whether BP control is associated with mortality and cardiovascular events (CVEs) among LTRs. We conducted a longitudinal cohort study of adult LTRs who survived to hospital discharge at a large tertiary care network between 2010 and 2016.
View Article and Find Full Text PDFEmerging resistance to current anti-malarials necessitates a more detailed understanding of the biological processes of Plasmodium falciparum proliferation, thus allowing identification of new drug targets. The well-conserved protein Receptor for Activated C-Kinase 1 (RACK1) was originally identified in mammalian cells as an anchoring protein for protein kinase C (PKC) and has since been shown to be important for cell migration, cytokinesis, transcription, epigenetics, and protein translation. The P.
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