Advances in cancer therapies have improved oncologic outcomes but can potentially expose patients to risk of cardiovascular toxicity. While left ventricular (LV) dysfunction is a well-known cardiotoxicity of cancer therapy. Pulmonary hypertension (PH) and right ventricular (RV) dysfunction are seen with several cancer therapies, including alkylating agents, tyrosine kinase inhibitors (TKIs), and immunotherapy, and are associated with significant morbidity and mortality.
View Article and Find Full Text PDFThe purpose of this study was to investigate the effect of different chemical intra-oral prosthesis cleansers on the surface properties of Parylene-C coated and non-coated polymethyl methacrylate (PMMA). A total of 120 PMMA samples were prepared. Half of the samples were coated with 10 µm of Parylene-C.
View Article and Find Full Text PDFStatement Of The Problem: The colonization of microorganisms on acrylic resin dentures may result in denture-induced stomatitis. No efficient coating has yet been proposed to address this issue.
Purpose: The purpose of this in vitro study was to assess the effect of various initial surface finishes and different Parylene coating thicknesses on the surface roughness (Ra) and surface free energy (SFE) of Parylene coated polymethyl methacrylate (PMMA).
The copy denture technique is a misnomer for the clinical and laboratory procedures involved in making complete dentures that replicate most of the features of the original prosthesis. The aim is to replicate the good features of an otherwise successful prosthesis that now requires replacement and to alter the poor features and so it is strictly speaking not a copy. There are many purported advantages to this technique which include reduced treatment time, increased patient acceptance especially for the elderly who may not adapt so well to a new prosthesis, maintenance of tooth position and vertical dimension.
View Article and Find Full Text PDFObjectives: Acrylic resins, used in the manufacturing of different types of intra-oral prostheses, are vulnerable to colonisation by microorganisms which potentially endanger the general health of the prostheses, wearers. The aim of this study was to investigate the influence of a novel coating (Parylene) on surface roughness of poly-methyl-methacrylate (PMMA) samples after simulated cleansing using an electric toothbrush and two brushing media (paste and pumice).
Methods: Fifty-six square PMMA samples were fabricated.