Publications by authors named "Steven N Lichtman"
Article Synopsis
- Fecal microbiota transplantation (FMT) is a procedure that transfers stool from a healthy donor to a patient in order to treat diseases, primarily used for recurrent Clostridium difficile infections but also being explored for other conditions.
- The study focuses on a child with D-lactic acidosis (D-LA), a metabolic disorder linked to an overproduction of D-lactate in the colon, leading to serious health issues; the child did not respond to standard treatments but improved after receiving FMT.
- The research includes analysis of the microbiota and lactic acid metabolites before and after FMT, offering insights into how D-LA develops and how FMT can help in its treatment.
Nineteen American infants aged less than three months developed persistent diarrhoea, acidosis, hypoalbuminaemia, and malnutrition, without evidence of enteric pathogens. Symptoms began 11-59 days before admission to the University of North Carolina Children's Hospital, and infants were fed semielemental formula. Despite further treatment with amino acid-based formula by continuous nasogastric infusion, diarrhoea persisted.
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