Hormone replacement therapy in brain-dead organ donors: a comprehensive review with an emphasis on traumatic brain injury.

Background: Organ shortage is an ongoing problem in the United States. Most donor organs are procured following brain death and a significant portion of brain-dead donors result from devastating brain injury. Without a standard practice for hormone replacement therapy (HRT) in the setting of brain death, a comprehensive review of the literature was deemed necessary.

Evaluation and management of the trauma patient for the interventional radiologist.

Interventional radiologists are adopting an increasingly important role in the evaluation and management of the acutely injured patient. The interventional radiologist may be called upon to provide services while hemorrhage is active, the patient is hemodynamically compromised, and a comprehensive trauma assessment is incomplete. The initial diagnostic and management approach to the trauma patient is optimally organized through the principles of advanced trauma life support.

Optimizing the respiratory pump: harnessing inspiratory resistance to treat systemic hypotension.

We review the physiology and affects of inspiration through a low level of added resistance for the treatment of hypotension. Recent animal and clinical studies demonstrated that one of the body's natural response mechanisms to hypotension is to harness the respiratory pump to increase circulation. That finding is consistent with observations, in the 1960s, about the effect of lowering intrathoracic pressure on key physiological and hemodynamic variables.