Publications by authors named "Steven Ho"

The Northeast Plain in China ranks among the top five regions that have been significantly impacted by haze pollution. To effectively control pollution, it is crucial to accurately assess the effects of emission reduction measures. In this study, we analyzed surveillance data and found substantial decreases (ranging from 19.

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New industrial parks, including fine chemical, medical manufacturers, etc., are emerging in modern cities in China, whereas their emissions and impacts have not been fully illuminated. In this study, ambient volatile organic compounds (VOCs) in Huizhou were measured in three functional zones, namely new industrial, roadside, and residential zones.

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  • Formaldehyde (HCHO) is a key factor in the formation of tropospheric ozone, with this study focusing on its effects in the Guanzhong Basin, Central China, examining both man-made and natural sources of emissions.
  • A severe ozone pollution incident in summer 2017 was modeled to analyze how ambient HCHO impacted ground-level ozone, revealing that secondary HCHO mainly contributed to high pollution levels, especially in the afternoons.
  • The research highlighted that biogenic emissions play a significant role in producing HCHO and that controlling nitrogen oxide emissions from industries and traffic is critical for reducing ozone pollution.
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  • * Seasonal variations in mean PM concentrations were noted, with higher levels typically found in winter and significant increases in inflammatory markers like interleukin 6 (IL-6) during summer.
  • * Correlation and mixed-effects model analyses demonstrated that endotoxin levels were positively associated with certain metals like chromium (Cr) and nickel (Ni), indicating that these metals could enhance the inflammatory response and toxicity related to endotoxin exposure, underscoring the need for effective air quality regulations.
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Nitroaromatic compounds (NACs) are important nitrogen organics in aerosol with strong light-absorbing and chemically reactive properties. In this study, NACs in six Chinese megacities, including Harbin (HB), Beijing (BJ), Xi'an (XA), Wuhan (WH), Chengdu (CD), and Guangzhou (GZ), were investigated for understanding their sources, gas-particle partitioning, and impact on BrC absorption properties. The concentrations of ΣNACs in PM in the six cities ranged from 9.

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This study investigated the determinants of personal exposures (PE) to coarse (PM) and fine particulate matter (PM) for elderly communities in Hong Kong. The mean PE PM and PM were 23.6 ± 10.

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Carbonaceous aerosols were collected in the valley city of Baoji city in Northern China in August 2022. The light absorption characteristics and influencing factors of black carbon (BC) and brown carbon (BrC) were analyzed, and their radiative forcing was estimated. The results showed that the light absorption of secondary brown carbon [Abs (370)] was 7.

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Polycyclic aromatic hydrocarbons (PAHs) in urban fugitive dust, known for their toxicity and ability to generate reactive oxygen species (ROS), are a major public health concern. This study assessed the spatial distribution and health risks of 15 PAHs in construction dust (CD) and road dust (RD) samples collected from June to November 2021 over the cities of Tongchuan (TC), Baoji (BJ), Xianyang (XY), and Xi'an (XA) in the Guanzhong Plain, China. The average concentration of ΣPAHs in RD was 39.

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In this study, online water-soluble inorganic ions were detected to deduce the formation mechanism of secondary inorganic aerosol in Xianyang, China during wintertime. The dominant inorganic ions of sulfate (SO), nitrate (NO), and ammonium (NH) (the sum of those is abbreviated as SNA) accounted for 17%, 21%, and 12% of PM mass, respectively. While the air quality deteriorated from excellent to poor grades, the precursor gas sulfur dioxide (SO) of SO increased and then decreased with a fluctuation, while nitrogen dioxide (NO) and ammonia (NH), precursors of NO and NH, and SNA show increasing trends.

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  • * Results showed that OVOC concentrations were higher in summer than in winter, with carbonyls and alcohols being the primary types identified, particularly acetone and methanol.
  • * The research indicated that controlling local OVOC sources like gasoline evaporation could help reduce these compounds and potentially lower ozone formation, benefiting air quality in Hong Kong.
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Oxygenated volatile organic compounds (OVOCs) play important roles in tropospheric chemistry, regulating the oxidation capacity and ozone (O) formation potential of the atmosphere. However, the evolution of OVOCs composition during vertical transport from the near surface to the upper atmosphere layer and the roles of OVOCs in the alpine atmospheric O formation are still poorly understood. In this study, we investigated the carbonyl compounds, the most important chemical group of OVOCs, and other gaseous pollutants simultaneously collected at the top (2060 m a.

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Personal exposure (PE) to polycyclic aromatic hydrocarbons (PAHs) and their derivatives in particulate matter with two aerodynamic sizes of 2.5 and 0.25 μm (PM and PM) from rural housewives was studied in the Fenwei Plain, China.

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  • - Methoxyphenols and nitroaromatic compounds (NACs) are harmful to both the atmosphere and human health, primarily emitted from the incomplete combustion of solid fuels, with their formation also influenced by photochemical reactions.
  • - A study using a potential aerosol mass-oxidation flow reactor found that emission factors for these compounds varied widely among different solid fuels, affected by factors like volatile matter and combustion conditions.
  • - Guaiacol and 4-nitro-2-vinylphenol were identified as tracers for organic aerosols, revealing that while biomass burning emitted more fresh guaiacol than coal, its aged emissions were similar, suggesting guaiacol may not be the most reliable biomass marker.
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As the importance of non-tailpipe particles (NTP) over tailpipe emissions from urban traffic has been increasing, there is a need to evaluate NTP contributions to ambient particulate matter (PM) using representative source profiles. The Brake and Tire Wear Study conducted in Los Angeles, California in the winter of 2020 collected 64 PM and 64 PM samples from 32 pairs of downwind-upwind measurements at two near-road locations (I-5 in Anaheim and I-710 in Long Beach). These samples were characterized for inorganic and organic markers and, along with locally-developed brake wear, tire wear, and road dust source profiles, subject to source apportionment using the effective-variance chemical mass balance (EV-CMB) model.

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  • * Vehicles with EURO 3 standards exhibited higher fresh emission factors for n-alkanes, and the emission factors for benzo [a]pyrene varied across different vehicles, highlighting inconsistencies in pollution outputs.
  • * High aged/fresh emission ratios for certain diacid compounds and strong correlations between toluene degradation and various acids suggest that photooxidation plays a crucial role in secondary organic aerosol formation, emphasizing the need for stricter vehicle emission regulations.
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  • - Tire and road wear microplastics (TRWMPs) are significant pollutants linked to motor vehicles, causing environmental and health concerns, with a study conducted in Xi'an, China, during summer 2019 revealing a total concentration of 6522 ± 1455 ng/m of various harmful chemicals.
  • - Phthalates were found to be the most abundant component in TRWMPs, making up nearly two-thirds of the total, and concentrations varied throughout the day, peaking during evening rush hour, suggesting factors beyond vehicle numbers, such as weather and road conditions, influence TRWMP levels.
  • - While the non-carcinogenic risks from TRWMPs were within safe limits, the carcinogenic
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  • * Results show significant reductions in indoor and personal PAH concentrations after switching to clean coal, with reductions of up to 93% for various PAH types, leading to improved pulmonary function.
  • * The findings suggest that using clean coal can substantially lower cancer risks associated with PAHs (by 60%-97%) and emphasizes the importance of transitioning to cleaner energy sources for better health outcomes.
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Background: Human papillomavirus (HPV) is the causative agent of nearly all forms of cervical cancer, which can arise upon viral integration into the host genome and concurrent loss of viral regulatory gene E2. Gene-based delivery approaches show that E2 reintroduction reduces proliferative capacity and promotes apoptosis in vitro.

Aims: This work explored if our calcium-dependent protein-based delivery system, TAT-CaM, could deliver functional E2 protein directly into cervical cancer cells to limit proliferative capacity and induce cell death.

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In this study, field measurement was conducted using an integrated online monitoring system to characterize heterogeneous properties and light absorption of refractory black carbon (rBC). rBC particles are mainly from the incomplete combustion of carbonaceous fuels. With the data collected from a single particle soot photometer, thickly coated (BC) and thinly coated (BC) particles are characterized with their lag times.

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Baoji is a medium-sized city in the Guanzhong Plain of northwest China. The compositions of three important organic groups, namely n-alkanes, polycyclic aromatic hydrocarbons (PAHs), and saccharides in atmospheric aerosol with different aerodynamic diameters in power were determined. Both seasonal and daily trends of the target organic chemical groups were demonstrated.

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Nitroaromatic compounds (NACs) are essential components of atmospheric organic aerosols. Coal combustion is a key source of atmospheric NACs. In this study, a triple-quadrupole liquid chromatography-mass spectrometry (LC-MS) system was used to identify ten individual NAC emitted in combustions of chunk coal and its briquette at different maturity levels.

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Volatile organic compounds (VOCs) and oxygenated VOCs (OVOCs) play important roles in atmospheric chemistry and are recognized as the major pollutants in roadside microenvironments of metropolitan Hong Kong, China. In this study, the ambient VOCs and OVOCs were intensively monitored at a roadside site in Hong Kong for one month during morning and evening rush hours. The emission characterizations, as well as ozone formation potentials (OFP) and hydroxyl radical (OH) loss rates (L) were determined.

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Particulate Matter (PM) concentrations near highways are influenced by vehicle tailpipe and non-tailpipe emissions, other emission sources, and urban background aerosols. This study collected PM and PM filter samples near two southern California highways (I-5 and I-710) over two weeks in winter 2020. Samples were analyzed for chemical source markers.

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We performed personal PM monitoring involving 56 adult residents in Hong Kong. Additionally, paired personal and residential indoor fine particle (PM) samples were collected from 26 homes and from 3 fixed monitoring locations (i.e.

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