Publications by authors named "Steven Duong"
Article Synopsis
- Programmed death 1 (PD-1) checkpoint inhibition shows good results in liver cancer but understanding other molecules that contribute to T-cell dysfunction is still limited.
- * A study analyzed CD8 T cells in a mouse liver cancer model, highlighting a distinct signature for exhausted T cells and the key role of the inhibitor receptor TIGIT in T-cell exhaustion.
- * Combining PD-1 inhibition with TIGIT-targeting antibodies enhanced the inhibition of liver cancer growth, suggesting TIGIT could be a valuable target for new cancer therapies.
Background And Objective: Goal was to evaluate the potential of in vivo optical coherence tomography (OCT) imaging to determine the response of patients with xerostomia to a dry mouth toothpaste versus fluoride toothpaste placebo.
Study Design/materials And Methods: Ten subjects with xerostomia participated in this double-blind, crossover, placebo-controlled study. After examination and OCT imaging, subjects used the first product for 15 days, followed by a 7-day washout period, and then they used the second product for 15 days.