Publications by authors named "Steven A Yarows"

Background: In 1974, the American Dental Association first considered recommending that dental offices measure blood pressure (BP) routinely, and it has been further encouraged since 2006. Investigators in several dental publications have recommended cancellation of dental procedures based solely on BP greater than 180/110 millimeters of mercury for urgent oral health care and greater than 160/100 mm Hg for elective oral health care, in the absence of prior medical consultation.

Methods: The authors reviewed the evidence for cancellation of any dental or surgical procedures by using an Ovid MEDLINE search for the terms dental, elevated blood pressure, and hypertension.

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Article Synopsis
  • Existing gout classification criteria are outdated and lack sensitivity and specificity, prompting the development of new guidelines.
  • An international group reviewed literature, performed diagnostic studies, and analyzed data to create and test these new criteria, focusing on the presence of MSU crystals as a key indicator.
  • The new criteria require at least one symptom of joint swelling or pain and demonstrate high sensitivity (92%) and specificity (89%), effectively incorporating modern imaging techniques and evidence.
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Objective: Existing criteria for the classification of gout have suboptimal sensitivity and/or specificity, and were developed at a time when advanced imaging was not available. The current effort was undertaken to develop new classification criteria for gout.

Methods: An international group of investigators, supported by the American College of Rheumatology and the European League Against Rheumatism, conducted a systematic review of the literature on advanced imaging of gout, a diagnostic study in which the presence of monosodium urate monohydrate (MSU) crystals in synovial fluid or tophus was the gold standard, a ranking exercise of paper patient cases, and a multicriterion decision analysis exercise.

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Purpose: To determine whether the HoMedics Walgreens Deluxe Arm Blood Pressure device (WGNBPA-540) meets the Association for the Advancement of Medical Instrumentation and the Working Group on Blood Pressure Monitoring of the European Society of Hypertension International Protocol accuracy requirements.

Materials And Methods: Simultaneous auscultatory measurements by two observers were obtained in individuals during measurement with the HoMedics WGNBPA-540. Each individual had three measurements after a minimum of 10 min of rest and 1 min between readings.

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Chronic activation of the renin-angiotensin-aldosterone system (RAAS) plays a key role in the development of hypertension, and cardiac and renal diseases. RAAS inhibitors, such as angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs), improve cardiovascular and renal outcomes. However, studies have shown that residual morbidity and mortality remains high, despite current optimal treatment.

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Introduction: Patients with stage 2 hypertension require large absolute reductions in blood pressure (BP) to achieve recommended BP goals. Combination therapy with the direct renin inhibitor, aliskiren, and the angiotensin receptor blocker, valsartan, has been shown to produce greater BP reductions than either agent alone in a double-blind study in 1797 hypertensive patients.

Methods: This post-hoc analysis evaluated the BP-lowering efficacy of aliskiren in combination with valsartan in a subset of patients (n=581) with stage 2 hypertension (baseline mean sitting systolic BP [msSBP] > or =160 mmHg).

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Purpose: To determine whether the HoMedics Model BPA-300 meets American Association for the Advancement of Medical Instrumentation (AAMI) accuracy standards.

Method: Simultaneous auscultatory measurements by two observers using a mercury manometer were obtained in participants during measurement with the HoMedics Model BPA-300. Triple measurements were obtained after a minimum of 5 min of rest and 1 min between readings.

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Background: The aim of this study was to assess dual renin system intervention with the maximum recommended doses of aliskiren and valsartan, compared with each drug alone in patients with hypertension.

Methods: In this double-blind study, 1797 patients with hypertension (mean sitting diastolic blood pressure 95-109 mm Hg and 8-h daytime ambulatory diastolic blood pressure > or =90 mm Hg) were randomly assigned to receive once-daily aliskiren 150 mg (n=437), valsartan 160 mg (455), a combination of aliskiren 150 mg and valsartan 160 mg (446), or placebo (459) for 4 weeks, followed by forced titration to double the dose to the maximum recommended dose for another 4 weeks. The primary endpoint was change in mean sitting diastolic blood pressure from baseline to week 8 endpoint.

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Background: To determine whether the Omron HEM637 wrist model with the wrist positioning sensor turned on (Son) is more accurate relative to upper arm auscultation by trained professionals than when the sensor was manually turned off (Soff).

Methods: Forty-four subjects, at least 30 years old, had repeated, sequential dual-observer upper arm auscultatory measurements (5 to 6 each) and oscillometric Omron HEM637 wrist measurements (4 each). Nineteen subjects were assigned to the wrist sensor On group and 25 were assigned to the wrist sensor Off group.

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