Publications by authors named "Steve Woods"
Article Synopsis
- The metabolic syndrome is linked to problems in both micro- and macrovascular systems, resulting in high blood pressure, but the mechanisms behind this are not fully understood.
- Research reveals that increased levels of leptin due to obesity can selectively expand the microvascular structure in brain regions that help regulate blood pressure.
- The study highlights that the HIF1α-VEGF signaling pathway in hypothalamic astrocytes is crucial for this process, indicating that disrupting this pathway can prevent obesity-related hypertension and sympathetic nervous system overactivity.
Purpose: The purpose of this study was to determine the early impact of American College of Surgeons (ACS)-level-1 verification at an established pediatric trauma center.
Methods: Following IRB approval, we conducted a retrospective review of all trauma patients treated at a level-1 state-designated pediatric trauma center, comparing 2years before (2009-2010) and 2years after ACS-verification (mid-2012-mid-2014). Statistical significance was defined as p<0.
Glucagon has long been known as a counter-regulatory hormone to insulin of fundamental importance to glucose homeostasis. Its prominent ability to stimulate glycogenolysis and gluconeogenesis, has historically cast this peptide as one hormone where the metabolic consequences of increasing blood glucose levels, especially in obesity, are viewed largely as being deleterious. This perspective may be changing in light of emerging data and reconsideration of historic studies, which suggest that glucagon has beneficial effects on body fat mass, food intake, and energy expenditure.
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