Publications by authors named "Steve Schoenfeld"
What Is This Summary About?: This is a summary of a paper published in a medical journal that describes the results of a study called POETYK PSO-1, which looked at a new treatment called deucravacitinib for plaque psoriasis. Plaque psoriasis appears on the body as round or oval raised patches (called plaques) typically covered by scales. This can cause the skin to itch, crack or bleed, and the associated itching and pain can make it difficult to perform basic everyday tasks.
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- Deucravacitinib, an oral treatment for moderate to severe plaque psoriasis, showed significantly better efficacy compared to placebo and apremilast in the phase 3 POETYK PSO-1 trial.
- Response rates at week 16 indicated that 58.4% of participants achieved a 75% reduction in psoriasis severity (PASI 75) with deucravacitinib, compared to only 12.7% with placebo and 35.1% with apremilast.
- The treatment was well tolerated, with adverse event rates similar to those seen with placebo and apremilast, although the study's one-year duration and limited racial diversity are noted as limitations.