Publications by authors named "Steve R Bennett"
Article Synopsis
- Researchers identified a new genetic locus (GLC1P) associated with normal tension glaucoma (NTG) on chromosome 12q14 through family linkage studies, showing a significant linkage score.
- They discovered a 780 kbp gene duplication within GLC1P that is inherited with NTG, and found that the genes in this duplication, including TBK1, are expressed in the human retina.
- Testing on various patient cohorts revealed that 1.3% of NTG patients showed duplications in GLC1P, particularly highlighting the TBK1 gene as potentially responsible for familial NTG, although further animal studies are needed to confirm these findings.
