Evidence for disruption in prefrontal cortical functions in juvenile bipolar disorder.

Objectives: Systematic parsing of executive function processes is critical for the development of more specific models of neurobiological processes mediating disturbed cognition in youth with bipolar disorder (BPD).

Methods: A sample of 33 children and adolescents with bipolar I disorder (BPD I) (mean age 12.1 +/- 3.

Declarative memory impairment in pediatric bipolar disorder.

Objectives: Impaired verbal declarative memory has been proposed as a trait marker for adult bipolar disorder. However, similar impairments in juvenile-onset bipolar disorder have not been yet documented. Here, we assessed declarative memory in a large sample of clinically well-characterized children with bipolar disorder.

A feasibility study of the childhood depression medication algorithm: the Texas Children's Medication Algorithm Project (CMAP).

Objective: To evaluate the feasibility and impact on clinical response and function associated with the use of an algorithm-driven disease management program (ALGO) for children and adolescents treated for depression with or without attention-deficit/hyperactivity disorder (ADHD) in community mental health centers.

Method: Interventions included (1). medication algorithms, (2).