Emerging evidence for the impact of Electric Vehicle sales on childhood asthma: Can ZEV mandates help?

Growing epidemiological studies indicate a significant fraction of asthma cases can be attributed to traffic-related air pollution (TRAP). Zero emission vehicle (ZEV) mandates-one of the most forward-looking climate policies in the United States-aim to reduce TRAP by mandating automakers to sell a certain fraction of Electric Vehicles (EVs) annually; however, their public health benefits are largely unknown. We conduct the screening step of the health impact assessment (HIA) of real-world EV sales to estimate the impact of ZEV mandates in reducing childhood asthma.

Investigating the functional implications of reinforcing feedback loops in transcriptional regulatory networks.

Transcription factors (TFs) and microRNAs (miRNAs) can jointly regulate transcriptional networks in the form of recurrent circuits or motifs. A motif can be divided into a feedforward loop (FFL) and a feedback loop (FBL). Incoherent FFLs have been the recent focus due to their potential to dampen gene expression noise in maintaining physiological norms.

On the lack of consensus over the meaning of openness: an empirical study.

This study set out to explore the views and motivations of those involved in a number of recent and current advocacy efforts (such as open science, computational provenance, and reproducible research) aimed at making science and scientific artifacts accessible to a wider audience. Using a exploratory approach, the study tested whether a consensus exists among advocates of these initiatives about the key concepts, exploring the meanings that scientists attach to the various mechanisms for sharing their work, and the social context in which this takes place. The study used a purposive sampling strategy to target scientists who have been active participants in these advocacy efforts, and an open-ended questionnaire to collect detailed opinions on the topics of reproducibility, credibility, scooping, data sharing, results sharing, and the effectiveness of the peer review process.