Hepatocellular Carcinoma: The Current Role of Surgical Intervention.

As the incidence of hepatocellular carcinoma (HCC) continues to rise, so does our understanding of this disease and the number of available treatment options and strategies. Although surgical intervention often continues to play a central role, it must be placed in the proper context of what has rapidly become a multimodality, multidisciplinary disease. Understanding the nuances of managing HCC and its associations and treatment options are essential for making appropriate surgical decisions.

Cholangiocarcinoma: aggressive surgical intervention remains justified.

Cholangiocarcinoma (CCA) continues to be a difficult disease to both diagnose and treat. Optimal treatment includes resection to histologically negative margins. In recent years, advanced imaging, including magnetic resonance cholangiography and endoscopic ultrasound, has presumably improved the accuracy of determining resectability.

Percutaneous liver biopsy after living donor liver transplantation resulting in fulminant hepatic failure: the first reported case of hepatic compartment syndrome.

A 28-year-old female who underwent live donor liver transplantation 3 years prior presented after percutaneous liver biopsy with abdominal and shoulder pain, nausea, vomiting, and elevated liver enzymes. Computed tomography (CT) showed an intrahepatic and subcapsular hematoma. There was a progressive increase in liver enzymes, bilirubin, and INR and a decline in hemoglobin.