[Comparison of 1-stage orthodontic bonding systems and 2-stage bonding systems: a review of the literature and the results of a randomized clinical trial].

Objective: The main objectives of this study are to present a literature review of self-etching primer's (SEP's) and present the outcomes of a prospective clinical trial to assess the clinical bond failure rates of orthodontic brackets bonded using a self-etching primer (SEP), compared with brackets bonded using a conventional acid-etched technique with a control adhesive (Transbond). A secondary aim was to investigate whether characteristics of the operator, patient or tooth bonded had any influence on bracket failure.

Design: Single-centre randomized controlled clinical trial.