Publications by authors named "Steve C Wallis"
Article Synopsis
- Catheter-associated urinary tract infections (CA-UTIs) are common hospital infections; this study evaluates the effectiveness of ciprofloxacin against these infections using an in vitro model.
- Researchers tested three standard bacterial strains and 45 clinical isolates to measure biofilm mass and bacterial density before and after treatment with ciprofloxacin.
- Results showed that while K. pneumoniae biofilms were more resistant to disruption, E. coli showed persistent growth in the bladder, and Pseudomonas aeruginosa had higher rates of ciprofloxacin resistance.
Background The aim of our work was to develop and validate a hydrophilic interaction liquid chromatography-electrospray ionization-tandem mass spectrometry (HILIC-ESI-MS/MS) methods for the quantification of tobramycin (TMC) and lincomycin (LMC)in plasma, microdialysis fluid and urine. Methods Protein precipitation was used to extract TMC and LMC from plasma, while microdialysis fluid and urine sample were diluted prior to instrumental analysis. Mobile phase A consisted of 2 mM ammonium acetate in 10% acetonitrile with 0.
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