Giant cell tumor of soft tissue arising in breast.

Primary giant cell tumor of soft tissue (GCT-ST) arising in breast is exceedingly rare. We report a case of a 60-year-old woman with a primary breast giant cell tumor that appeared histologically identical to giant cell tumor of bone and had a clinically malignant course. The patient presented with a cystic mass of the breast, suspected on imaging to be an organizing hematoma, possibly related to previous injury.

Oral-cutaneous CD4-positive T-cell lymphoma: a study of two patients.

We describe two slowly progressive cases of T-cell lymphoma that involved both acral skin and oral cavity. One patient presented with a tongue nodule, completely responded to chemotherapy and then developed recurrent lymphoma involving tongue and skin a few months later that also responded to therapy. The second patient presented with a skin nodule that spontaneously resolved without therapy, and subsequently recurred in tongue and skin a few years later.

Follicular hybrid cysts with infundibular, isthmic-catagen, and pilomatrical differentiation: a report of 2 patients.

The term hybrid cyst was originally coined to describe combination follicular cysts with both epidermoid and trichilemmal (pilar) epithelial zones, separated by an abrupt transition. The concept has since expanded to include many different combinations of pilosebaceous unit differentiation. Entities previously reported also include infundibular and pilomatricomal cyst, trichilemmal and pilomatricomal cyst, eruptive vellus hair cyst combined with steatocystoma or trichilemmal cyst, and trichilemmal, sebaceous, and pilomatricomal cyst.

Cutaneous lymphoid hyperplasia and marginal zone B-cell lymphoma following vaccination.

Atypical lymphoid infiltrations arose within the influenza inoculation sites of two adult female patients. One patient developed a low-grade cutaneous marginal zone B-cell lymphoma (MZL) that was responsive to local excision and radiation therapy despite spread to a distant cutaneous site. The second patient's clinical course was characterized by a locally aggressive, histologically reactive inflammatory reaction responsive only to radiation therapy after multiple failed attempts at surgical resection.