The prognostic significance of e-cadherin in papillary thyroid carcinoma was evaluated in a retrospective study. From September 1985 to December 1996, 113 patients underwent surgery for papillary thyroid carcinoma. Seventy-eight formalin-fixed, paraffin-embedded tissue samples were available for immunohistochemical analysis of e-cadherin expression.
View Article and Find Full Text PDFSurgical excision is the treatment of choice for differentiated thyroid carcinoma. Because no prospective randomized clinical trials are available, decisions regarding the extent of surgical resection and the mode of lymph node dissection must be made on the basis of imperfect retrospective data. Recommendations for surgical strategy in differentiated thyroid cancer are discussed.
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