Decreased Symptoms without Augmented Skin Blood Flow in Subjects with RLS/WED after Vibration Treatment.

Study Objectives: Vascular disturbances leading to tissue hypoxia have been named as a possible cause for RLS/WED. Vibration to the whole body (WBV) in subjects with RLS/WED results in increased skin blood flow (SBF). The aims of this investigation were to (1) determine if a two-week treatment with WBV will decrease symptoms associated with RLS/WED and, (2) if so, determine if the mechanism for improvement in symptoms is related to an increase in SBF, as measured in flux.

Performance on the Functional Movement Screen in older active adults.

Background: The Functional Movement Screen (FMS™) has become increasingly popular for identifying functional limitations in basic functional movements. This exploratory and descriptive study was undertaken to confirm feasibility of performing the FMS™ in older active adults, assess prevalence of asymmetries and to evaluate the relationship between functional movement ability, age, physical activity levels and body mass index (BMI).

Methods: This is an observational study; 97 men ( = 53) and women ( = 44) between the ages of 52 and 83 participated.

Restless legs syndrome and near-infrared light: An alternative treatment option.

There are few treatment options in managing restless legs syndrome (RLS); the most frequently used are dopaminergic drugs and movement. New treatment options are highly sought after. This study evaluated the effectiveness of monochromatic near-infrared light treatment in decreasing symptoms associated with RLS.

Neurophysiological reflex mechanisms' lack of contribution to the success of PNF stretches.

Background And Purpose: Proprioceptive neuromuscular facilitation (PNF) stretches are widely used in athletics and rehabilitation. Although it has been shown that they produce better range-of-motion (ROM) increases than the slow or static stretch, the mechanisms responsible remain an enigma. This study was conducted to determine whether the previously proposed neurophysiological mechanisms of reciprocal inhibition and autogenic inhibition are responsible for the success of PNF stretches.

Improvement in clinical markers in CF patients using a reduced glutathione regimen: an uncontrolled, observational study.

CFTR mutation, which causes cystic fibrosis (CF), has also recently been identified as causing glutathione system dysfunction and systemic deficiency of reduced glutathione (GSH). Such dysfunction and deficiency regarding GSH may contribute to the pathophysiology of CF. We followed 13 patients (age range 1-27 years) with cystic fibrosis who were using a regimen of reduced glutathione (GSH), including oral glutathione and inhaled buffered glutathione in an uncontrolled, observational study.

Acute stretch perception alteration contributes to the success of the PNF "contract-relax" stretch.

Context: Some researchers have suggested that an alteration of stretch perception could be responsible for the success of the contract-relax (CR) stretch, a stretch technique derived from proprioceptive neuromuscular facilitation (PNF).

Objective: This study was conducted to determine if the alteration of the stretch perception is a possible explanation for the range of motion (ROM) gains of the CR stretch.

Participants: Eighteen subjects performed two stretches in randomized order: the slow stretch and the CR stretch.

A pilot study of the effect of inhaled buffered reduced glutathione on the clinical status of patients with cystic fibrosis.

Study Objectives: To assess the impact of inhaled, buffered reduced glutathione (GSH) on clinical indicators of cystic fibrosis (CF) pathophysiology.

Design And Patients: A randomized, double-blind, placebo-controlled pilot study was conducted over an 8-week period. Nineteen subjects, age 6 to 19 years, with CF status documented by positive sweat chloride test results (> 60 mEq/L) were recruited for the trial.

Impact of the LDS church's health doctrine on deaths from diseases and conditions associated with cigarette smoking.

Purpose: This study provides a quantitative assessment of the impact the LDS Church's health doctrine has on deaths and years of potential life lost (YPLL) from diseases and conditions associated with cigarette smoking in Utah.

Methods: Pooled estimates of relative risk from review articles and meta-analyses in combination with 1996 Utah smoking prevalence data were used to calculate smoking-attributed etiologic fractions, deaths, and YPLL.

Results: Numbers of deaths attributed to smoking between 1994 and 1998 in Utah are 1730 for LDS men, 721 for LDS women, 1739 for non-LDS men, and 1138 for non-LDS women.

Toward a better understanding of the comparatively high prostate cancer incidence rates in Utah.

Background: This study assesses whether comparatively high prostate cancer incidence rates among white men in Utah represent higher rates among members of the Church of Jesus Christ of Latter-day Saints (LDS or Mormons), who comprise about 70% of the state's male population, and considers the potential influence screening has on these rates.

Methods: Analyses are based on 14,693 histologically confirmed invasive prostate cancer cases among men aged 50 years and older identified through the Utah Cancer Registry between 1985 and 1999. Cancer records were linked to LDS Church membership records to determine LDS status.

Maternal stress and affect influence fetal neurobehavioral development.

The authors investigated the association between maternal psychological and fetal neurobehavioral functioning. Data were provided by 52 maternal-fetal pairs at 24, 30, and 36 weeks gestation. The relations between maternal measures and fetal heart rate, variability, and motor activity were statistically modeled.