Trabeculectomy using mitomycin C versus an atelocollagen implant: clinical results of a randomized trial and histopathologic findings.

Purpose: To assess the efficacy of trabeculectomy with a biodegradable Ologen™ implant (OLO) versus mitomycin C (MMC) in patients in a prospective randomized clinical trial.

Methods: In the MMC group (15 patients), trabeculectomy was performed according to standard protocols. In the OLO group (15 patients) after standard trabeculectomy, the implant was positioned on top of the scleral flap, and no MMC was applied.

Previous cyclodestruction is a risk factor for late-onset hypotony and suprachoroidal haemorrhage after glaucoma drainage device surgery.

Aim: To investigate whether previous cyclodestructive (eg, cyclophotocoagulation and cyclocryodestruction) procedures have any influence on the general outcome and pressure level after glaucoma drainage device (GDD) surgery.

Methods: Retrospective analysis of 110 consecutive patients who had undergone GDD (Baerveldt 250 mm(2) and 350 mm(2) implant, AMO, USA) surgery with a minimum follow-up of 3 months. The patients were divided into patients with previous cyclodestructive surgery before GDD surgery (I; 47 patients) and patients without previous cyclodestructive surgery (II; 63 patients).

Clinical use of a new position-independent rebound tonometer.

Purpose: To compare intraocular pressure (IOP) measurements obtained by rebound tonometry (Icare PRO tonometer), applanation tonometry (Goldmann and Perkins tonometry), and dynamic contour tonometry in the upright and the supine positions, and to investigate the influence of axial length and central corneal thickness.

Methods: Ninety-nine right eyes of 99 patients with glaucoma or suspect for glaucoma, admitted to our department between November 2010 and January 2011 to obtain an IOP profile including supine measurements, were included in our study. IOP measurements were obtained in an upright position using an Icare PRO rebound (RTPRO), a Goldmann applanation (GAT), and a Pascal dynamic contour tonometer (DCT).

A new rebound tonometer for home monitoring of intraocular pressure.

Background: To compare intraocular pressure (IOP) measurements obtained by the Icare ONE rebound tonometer (RTONE) and the Goldmann applanation tonometer (GAT) in healthy persons and glaucoma patients in a prospective study, and to investigate the influence of central corneal thickness (CCT).

Methods: Measurements on 126 right eyes were obtained by three equally skilled ophthalmologists with each of the above-mentioned tonometers. In addition, patients measured their own IOP with the RTONE (RTONE(p)).