A prospective randomized trial comparing intraoperative 5-fluorouracil vs mitomycin C in primary trabeculectomy.

Purpose: To compare the safety and efficacy of intraoperative 5-fluorouracil (5-FU) or Intraoperative mitomycin C (MMC) in eyes undergoing primary trabeculectomy.

Design: Prospective double-masked randomized clinical trial.

Methods: One hundred fifteen eyes of 103 patients with uncontrolled intraocular pressure (IOP) despite maximally tolerated medical therapy or laser were prospectively randomized in a double-masked fashion to one of two treatment groups in a single institution setting.

Conjunctival advancement versus nonincisional treatment for late-onset glaucoma filtering bleb leaks.

Objective: To compare the outcomes of conjunctival advancement and nonincisional management of late-onset glaucoma filtering bleb leak.

Design: Retrospective, nonrandomized, comparative interventional trial.

Participants: Fifty-one eyes of 48 persons who underwent management of late-onset glaucoma filtering bleb leak from December 1986 through December 1999 were included.